Pneumococcal vaccines in China.

IF 3.5 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Human Vaccines & Immunotherapeutics Pub Date : 2025-12-01 Epub Date: 2025-01-30 DOI:10.1080/21645515.2025.2460274
Shanshan Wang, Bin Li, Qiong Chen, Chune Wang, Bin Wang, Qiang Ye, Yinghua Xu
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Abstract

Invasive pneumococcal disease (IPD) is a serious global public health problem and the leading cause of morbidity and mortality in children and adults in China. Thus, developing and administering pneumococcal vaccines are important for disease prevention. The PPV23 and PCV13 vaccines are available in the Chinese market and are primarily produced by domestic manufacturers. The potential risk of increased IPD caused by non-vaccine serotypes should be considered. Here, we review the current status of IPD, pneumococcal vaccines, and their quality control in China. We also address the challenges and future directions for making progress in controlling IPD, emphasizing the need for further evaluation of the disease burden and monitoring the effectiveness of vaccination efforts.

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中国的肺炎球菌疫苗。
侵袭性肺炎球菌病(IPD)是一个严重的全球公共卫生问题,也是中国儿童和成人发病率和死亡率的主要原因。因此,开发和接种肺炎球菌疫苗对疾病预防非常重要。PPV23和PCV13疫苗已在中国市场上市,主要由国内制造商生产。应考虑由非疫苗血清型引起的IPD增加的潜在风险。本文综述了IPD、肺炎球菌疫苗及其质量控制在中国的现状。我们还讨论了在控制IPD方面取得进展的挑战和未来方向,强调需要进一步评估疾病负担和监测疫苗接种工作的有效性。
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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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