Solitary Fibrous Tumor of the Tongue: a Case Report.

IF 3.2 Q2 PATHOLOGY Head & Neck Pathology Pub Date : 2025-01-30 DOI:10.1007/s12105-024-01738-y

Anne Evelyn Oliveira Moura, Evelyne Pedroza de Andrade, Thiago Coelho Gomes da Silva, Danielle Machado Farias, Pablo Agustin Vargas, Elaine Judite de Amorim Carvalho, Danyel Elias da Cruz Perez

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引用次数: 0

Abstract

Introduction: Solitary fibrous tumor (SFT) is a fibroblastic neoplasm of uncertain biological origin that is rare in the tongue.

Case report: A 42-year-old woman presented with a painless, submucosal nodule in the tongue. Based on the clinical hypothesis of benign mesenchymal neoplasia, the lesion was excised, and the specimen was submitted for histopathological analysis. Microscopically, a proliferation of spindle cells with a patternless arrangement was observed, separated by dilated and angulated vascular spaces. Immunohistochemical analysis revealed positivity for CD34, CD99, Bcl-2, Ki-67 (< 5%), and negativity for S-100. Additionally, the tumor cells showed a positive nuclear reaction for STAT6. The diagnosis was a solitary fibrous tumor.

Conclusions: This report presents a case of SFT in the tongue, emphasizing its clinicopathological, microscopic, and immunohistochemical features.

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来源期刊

Head & Neck Pathology PATHOLOGY-

CiteScore

5.70

自引率

9.50%

发文量

期刊介绍： Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.