Myofibrillar Myopathy

IF 1.5 3区 农林科学 Q3 VETERINARY SCIENCES Veterinary Clinics of North America-Equine Practice Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI:10.1016/j.cveq.2024.11.005
Stephanie J. Valberg DVM, PhD , Zoë J. Williams DVM, PhD
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肌纤维肌病。
肌原纤维性肌病(MFM)的特征是肌原纤维的节段性紊乱和一种称为desmin的蛋白质的异位积累。MFM以前被认为是一种糖原储存病,现在被认为是一种独立的肌病。患有MFM的耐力阿拉伯人通常在比赛结束时表现为劳损性横纹肌溶解(MFM- er),血清肌酶升高和肌红蛋白尿。温血马MFM (MFM- wb)通常表现出与疼痛相关的行为,如运动不耐受,不愿使用后四分之一肌肉,移动跛行和正常的血清肌肉酶。两种形式都有基于半胱氨酸的抗氧化剂减少的证据,此外,MFM-WB具有不适应训练反应的分子特征。
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来源期刊
CiteScore
2.10
自引率
9.10%
发文量
55
审稿时长
>36 weeks
期刊介绍: Veterinary Clinics of North America: Equine Practice presents those in the veterinary medicine field with the most current treatment of horses, updates on the latest advances, and provides a sound basis for choosing treatment options. Published 3 times a year—in April, August, and December—each issue features expert, state-of-the-art reviews on a single topic in equine practice, including gastroenterology, imaging, infectious diseases, nutrition, orthopedics, pathology, pharmacology and therapeutics, and surgery.
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