[Community acquired bacterial meningitis in adults].

IF 0.6 Innere Medizin (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-31 DOI:10.1007/s00108-025-01851-2
Marie Madlener, Insa Joost
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Abstract

Bacterial meningitis is a rare but severe disease with a high mortality. The most frequent pathogens in adults are pneumococcus, meningococcus and Listeria. The most important key symptoms are headache, meningism and fever; however, the absence of individual cardinal symptoms does not exclude the diagnosis. The empirical treatment consists of ceftriaxone and ampicillin, supplemented with dexamethasone as needed. It should be initiated without delay if bacterial meningitis is suspected. Before this, two pairs of blood cultures should be obtained followed by a lumbar puncture. An elevated intracranial pressure must be excluded via cerebral computed tomography before performing a lumbar puncture only in patients with confirmation of impaired consciousness, focal neurological deficits or epileptic seizures. In such cases treatment is initiated immediately after obtaining blood cultures but before the lumbar puncture. The identification and management of a focus are essential and should be conducted on the day of admission.

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[成人社区获得性细菌性脑膜炎]。
细菌性脑膜炎是一种罕见但严重的疾病,死亡率很高。成人最常见的病原体是肺炎球菌、脑膜炎球菌和李斯特菌。最重要的关键症状是头痛、脑膜炎和发烧;然而,没有个别的主要症状并不排除诊断。经验治疗包括头孢曲松和氨苄西林,根据需要补充地塞米松。如果怀疑是细菌性脑膜炎,应立即进行治疗。在此之前,应进行两对血培养,然后进行腰椎穿刺。只有在确认意识受损、局灶性神经缺陷或癫痫发作的患者行腰椎穿刺前,必须通过大脑计算机断层扫描排除颅内压升高。在这种情况下,治疗在获得血培养后立即开始,但在腰椎穿刺之前。重点的识别和管理是至关重要的,应该在入院当天进行。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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