What is new in metabolic dysfunction-associated steatotic liver disease?

IF 3 3区 医学 Q2 ENDOCRINOLOGY & METABOLISM Journal of Diabetes Investigation Pub Date : 2025-02-01 DOI:10.1111/jdi.70003
Kathryn CB Tan
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Abstract

The change in nomenclature from nonalcoholic fatty liver disease to metabolic dysfunction associated-steatotic liver disease has emphasized the importance of metabolic abnormalities in this liver disorder. New pharmacological therapy has recently become available and resmetirom, a thyroid hormone receptor agonist, has received approval for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis and significant liver fibrosis.

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代谢功能障碍相关的脂肪变性肝病有什么新进展?
从非酒精性脂肪性肝病到代谢功能障碍相关的脂肪变性肝病的命名变化强调了代谢异常在这种肝脏疾病中的重要性。最近出现了新的药物治疗方法,雷司替罗,一种甲状腺激素受体激动剂,已被批准用于治疗非肝硬化代谢功能障碍相关的脂肪性肝炎和显著肝纤维化。
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来源期刊
Journal of Diabetes Investigation
Journal of Diabetes Investigation ENDOCRINOLOGY & METABOLISM-
CiteScore
6.50
自引率
9.40%
发文量
218
审稿时长
6-12 weeks
期刊介绍: Journal of Diabetes Investigation is your core diabetes journal from Asia; the official journal of the Asian Association for the Study of Diabetes (AASD). The journal publishes original research, country reports, commentaries, reviews, mini-reviews, case reports, letters, as well as editorials and news. Embracing clinical and experimental research in diabetes and related areas, the Journal of Diabetes Investigation includes aspects of prevention, treatment, as well as molecular aspects and pathophysiology. Translational research focused on the exchange of ideas between clinicians and researchers is also welcome. Journal of Diabetes Investigation is indexed by Science Citation Index Expanded (SCIE).
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Issue Information Issue Information The biology of PKM2 in the metabolism and senescence in diabetic kidney disease Letter to the Editor in response to the article “Prediction of future insulin deficiency in glutamic acid decarboxylase autoantibody enzyme-linked immunosorbent assay-positive patients with slowly progressive type 1 diabetes” Advances in insulin pump systems lead to stepwise improvements in treatment satisfaction in people with type 1 diabetes: A single-center retrospective study
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