Experience in setting up non-robotic minimally invasive direct coronary artery bypass grafting in a non-routine off-pump coronary artery bypass center.

IF 3.4 3区 医学 Q2 MEDICINE, RESEARCH & EXPERIMENTAL European Journal of Medical Research Pub Date : 2025-01-31 DOI:10.1186/s40001-025-02320-0
Yukiharu Sugimura, Tomoyuki Suzuki, Sebastian Johannes Bauer, Friederike Irmgard Schoettler, Moritz Benjamin Immohr, Michael André Maliwa, Arash Mehdiani, Lachmandath Tewarie, Gereon Schaelte, Ajay Moza, Payam Akhyari
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引用次数: 0

Abstract

Background: The safety of minimally invasive direct coronary artery bypass (MIDCAB) has been proven. Nevertheless, reports on clinical outcomes in MIDCAB and the learning curve of this challenging technique in a non-routine off-pump coronary artery bypass (OPCAB) center are still limited. Here, we introduce our clinical outcomes of non-robotic MIDCAB.

Methods: Between August 2022 and March 2024, 72 consecutive patients with a mean age of 67.4 ± 9.5 years underwent non-robotic MIDCAB (defined as off-pump bypass grafting of the left internal mammary artery to the left anterior descending artery through left-sided mini-thoracotomy). We analyzed operation time and incidence of major adverse cardiac and cerebrovascular events (MACCE). Further, subgroup analyses included body mass index (BMI) with a cut-off of 30 kg/m2 [BMI ≧ 30: n = 18 (25.0%)] and body surface area (BSA) with a cut-off of 2.0 m2 [BSA ≧ 2.0: n = 34 (47.2%)].

Results: All patients survived, whereas MACCE occurred in 4 patients (5.6%). By correlation analyses, no learning curve for operation time was observed in all cases analysis (p = 0.79), but MACCE (n = 4, 5.6%) exclusively observed in the first 34 patients. Furthermore, BMI ≧ 30 or BSA ≧ 2.0 was not significantly related to longer operation time (p = 0.42 and p = 0.52, respectively) and MACCE (p = 0.26 and p = 0.35, respectively). In addition, body size had no effect on operation time according to multiple regression analysis (p = 0.36).

Conclusions: Our study suggested that implementing non-robotic MIDCAB can be safely accomplished at a center with no previous routine in OPCAB surgery, even for patients with bigger body sizes. MACCE occurs more frequently in the early stages when adopting this surgical technique.

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非机器人微创直接冠状动脉旁路移植术在非常规非体外循环冠状动脉旁路移植术中心的应用经验。
背景:微创直接冠状动脉搭桥术(MIDCAB)的安全性已得到证实。然而,关于MIDCAB的临床结果和这项具有挑战性的技术在非常规非体外循环冠状动脉搭桥(OPCAB)中心的学习曲线的报道仍然有限。在这里,我们介绍我们的非机器人MIDCAB的临床结果。方法:在2022年8月至2024年3月期间,连续72例平均年龄67.4±9.5岁的患者接受了非机器人MIDCAB(定义为通过左侧小开胸将左乳内动脉旁路移植术至左前降支)。我们分析手术时间和主要心脑血管不良事件(MACCE)的发生率。此外,亚组分析包括身体质量指数(BMI),临界值为30 kg/m2 [BMI≧30:n = 18(25.0%)]和体表面积(BSA),临界值为2.0 m2 [BSA≧2.0:n = 34(47.2%)]。结果:所有患者均存活,4例(5.6%)发生MACCE。通过相关分析,所有病例均未观察到手术时间的学习曲线(p = 0.79),但仅在前34例患者中观察到MACCE (n = 4, 5.6%)。BMI≧30或BSA≧2.0与手术时间(p = 0.42、p = 0.52)及MACCE (p = 0.26、p = 0.35)无显著相关。经多元回归分析,体型对手术时间无影响(p = 0.36)。结论:我们的研究表明,在没有OPCAB手术常规的中心,即使对于体型较大的患者,实施非机器人MIDCAB也可以安全完成。当采用这种手术技术时,MACCE更常发生在早期阶段。
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来源期刊
European Journal of Medical Research
European Journal of Medical Research 医学-医学:研究与实验
CiteScore
3.20
自引率
0.00%
发文量
247
审稿时长
>12 weeks
期刊介绍: European Journal of Medical Research publishes translational and clinical research of international interest across all medical disciplines, enabling clinicians and other researchers to learn about developments and innovations within these disciplines and across the boundaries between disciplines. The journal publishes high quality research and reviews and aims to ensure that the results of all well-conducted research are published, regardless of their outcome.
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