Pilot screening for prodromal Parkinson's disease in post-9/11 Veterans with probable rapid eye movement sleep behavior disorder

IF 3.4 3区 医学 Q2 CLINICAL NEUROLOGY Parkinsonism & related disorders Pub Date : 2025-03-01 Epub Date: 2025-01-26 DOI:10.1016/j.parkreldis.2025.107309
Melissa B. Jones , Dakota Broadway , Taryn White , George R. Jackson , Supriya Singh , Ruosha Li , Erik K. St Louis , Laura E. Marsh , Ricardo E. Jorge
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Abstract

This pilot examined prodromal markers in post-9/11 Veterans with TBI and probable REM sleep behavior disorder (N = 12). RBD was confirmed in 5 of 10 (50 %) participants with polysomnography. Veterans with subthreshold parkinsonism had lower olfactory scores. Future studies should quantify REM sleep without atonia and include broader markers.
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9/11后可能有快速眼动睡眠行为障碍的退伍军人前驱帕金森病的试点筛查
本试验检查了9/11后创伤性脑损伤和可能的快速眼动睡眠行为障碍退伍军人的前驱症状标记(N = 12)。10名多导睡眠图参与者中有5名(50%)被证实RBD。患有阈下帕金森症的退伍军人嗅觉得分较低。未来的研究应该量化无张力的快速眼动睡眠,并包括更广泛的标记。
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来源期刊
Parkinsonism & related disorders
Parkinsonism & related disorders 医学-临床神经学
CiteScore
6.20
自引率
4.90%
发文量
292
审稿时长
39 days
期刊介绍: Parkinsonism & Related Disorders publishes the results of basic and clinical research contributing to the understanding, diagnosis and treatment of all neurodegenerative syndromes in which Parkinsonism, Essential Tremor or related movement disorders may be a feature. Regular features will include: Review Articles, Point of View articles, Full-length Articles, Short Communications, Case Reports and Letter to the Editor.
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