Prevalence and determinants of low birth weight in Ethiopia: A multilevel meta-analysis and systematic review

IF 3.2 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Public Health Pub Date : 2025-02-01 DOI:10.1016/j.puhe.2024.12.044
Samuel Derbie Habtegiorgis , Lake Kumlachew , Adane Tesfaye , Molla Azmeraw , Eyerus Tesfaw , Animut Takele Telayneh , Adane Adugna , Friehiwot Molla , Molla Yigzaw Birhanu , Kalkidan Worku Mitiku
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Abstract

Objectives: Worldwide in 2015, approximately 20.5 million infants were born underweight, with Sub-Saharan Africa and Asia bearing the highest burden. Numerous studies have investigated low birth weight (LBW) and its contributing factors in Ethiopia, enlightening notable variations in reported prevalence and associated factors. The goal of this study was to estimate the pooled prevalence of LBW and identify determinants using a multilevel meta-analytic approach.

Study design

A multilevel meta-analysis was conducted with R (version 4.4.0) using the metafor package.

Methods

We searched the PubMed/MedLine, Google Scholar, and Cochrane databases from January 2018 to May 2024. multilevel random effects model, with the restricted maximum likelihood method used by accounting for the nested structure of the data, with studies nested within clusters.

Results

The pooled proportion of low birth weight based on the three-level meta-analysis model was 0.36 (95%CI: 0.32–0.39; p < 0.0001). The estimated variance components were Level3 = 5.13 % and Level2 = 92.30 %. Subgroup analyses were done based on different factors. However, there is no significant difference between groups.
maternal age (OR: 2.46; 95 % CI: 1.96 to 3.09), AnteNatal Care follow-up (OR: 3.00; 95 % CI: 1.86 to 4.84), Gestational Age (OR: 9.68; 95 % CI: 5.88 to 15.94), Birth Interval (OR: 3.97; 95 % CI: 1.13 to 13.97), Pregnancy Induced Hypertension (OR: 2.83; 95 % CI: 1.34 to 5.97), and maternal anaemic status (OR: 3.32 95 % CI: 1.14 to 9.69) were the possible factors.

Conclusions

This study found a 36 % double arcsin transformed proportion of low birth weight, with significant factors including maternal age, ANC follow-up, gestational age, birth interval, pregnancy-induced hypertension, and maternal anaemia. Interventions like promoting a good diet, sufficient antenatal care, and maintaining a clean environment are needed to meet global nutrition goals by 2025.
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埃塞俄比亚出生体重不足的流行率和决定因素:多层次荟萃分析和系统综述。
目标:2015年,全世界约有2050万婴儿出生时体重不足,其中撒哈拉以南非洲和亚洲负担最重。许多研究调查了埃塞俄比亚的低出生体重(LBW)及其影响因素,揭示了报告的患病率和相关因素的显著差异。本研究的目的是估计LBW的总患病率,并使用多层次荟萃分析方法确定决定因素。研究设计:使用R(版本4.4.0)进行多水平荟萃分析,使用元软件包。方法:检索2018年1月至2024年5月的PubMed/MedLine、谷歌Scholar和Cochrane数据库。多层随机效应模型,考虑到数据的嵌套结构,采用限制最大似然法,研究嵌套在聚类内。结果:基于三水平荟萃分析模型的低出生体重合并比例为0.36 (95%CI: 0.32-0.39;p3 = 5.13%, Level2 = 92.30%。根据不同因素进行亚组分析。但两组间无显著差异。产妇年龄(OR: 2.46;95% CI: 1.96 ~ 3.09),产前保健随访(OR: 3.00;95% CI: 1.86 - 4.84),胎龄(OR: 9.68;95% CI: 5.88 ~ 15.94),出生间隔(OR: 3.97;95% CI: 1.13 ~ 13.97),妊娠高血压(OR: 2.83;95% CI: 1.34 ~ 5.97)和母亲贫血状态(OR: 3.32 95% CI: 1.14 ~ 9.69)是可能的因素。结论:本研究发现低出生体重双弧度转化比例为36%,其显著因素包括产妇年龄、ANC随访、胎龄、分娩间隔、妊高征和产妇贫血。要在2025年之前实现全球营养目标,就需要促进良好饮食、充分的产前保健和保持清洁环境等干预措施。
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来源期刊
Public Health
Public Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
7.60
自引率
0.00%
发文量
280
审稿时长
37 days
期刊介绍: Public Health is an international, multidisciplinary peer-reviewed journal. It publishes original papers, reviews and short reports on all aspects of the science, philosophy, and practice of public health.
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