Des ulcérations du cuir chevelu et de la jambe révélant une sarcoïdose systémique

IF 0.9 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Revue De Medecine Interne Pub Date : 2025-03-01 DOI:10.1016/j.revmed.2025.01.004
Houria Sahel , Billel Merrouche , Nacima Djennane , Amine Hebouchi , Ammar Maireche
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Abstract

Introduction

Sarcoidosis is a multisystem disorder. Skin injury can have a wide range of semiologies. Ulcerated forms have rarely been described.

Case report

A 56-year-old woman was operated on for a scalp mass. The pathological study shows tuberculoid granulomas with caseous necrosis of the right temporalis muscle. Two years later, she consulted for ulcerations of the scalp and right leg. Histological examination of the scalp lesion and a back lesion showed gigantocellular granulomas without caseous necrosis. Thoraco-abdomino-pelvic CT scan revealed hilar and abdominopelvic lymphadenopathy. On brain magnetic resonance imaging, signs of myositis of the right temporalis muscle involvement were noted. The diagnosis of ulcerated multisystem sarcoidosis was made. A spectacular improvement was noted after seven months of treatment with systemic prednisone, without recurrence after three years.

Conclusion

We report an original observation of cutaneous ulcerations revealing multisystemic sarcoidosis. Diagnosis of this rare form relies on skin biopsy and exclusion of other cutaneous granulomatoses. The evolution of ulcerative sarcoidosis is usually satisfactory with the usual treatments of sarcoidosis.
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[头皮和腿部溃疡显示系统性结节病]。
结节病是一种多系统疾病。皮肤损伤可以有广泛的符号学。溃疡的形式很少被描述。病例报告:一名56岁妇女因头皮肿块手术。病理检查显示右颞肌结核样肉芽肿伴干酪样坏死。两年后,她因头皮和右腿溃疡就诊。头皮和背部病变的组织学检查显示巨大细胞肉芽肿,无干酪样坏死。胸腹盆腔CT扫描显示肺门及腹腔淋巴结肿大。在脑磁共振成像上,右颞肌肌炎的征象被注意到。诊断为溃疡性多系统结节病。全身性强的松治疗7个月后显著改善,3年后无复发。结论:我们报告一个原始的观察皮肤溃疡显示多系统结节病。诊断这种罕见的形式依赖于皮肤活检和排除其他皮肤肉芽肿。溃疡性结节病的发展通常对结节病的常规治疗是满意的。
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来源期刊
Revue De Medecine Interne
Revue De Medecine Interne 医学-医学:内科
CiteScore
0.70
自引率
11.10%
发文量
526
审稿时长
37 days
期刊介绍: Official journal of the SNFMI, La revue de medecine interne is indexed in the most prestigious databases. It is the most efficient French language journal available for internal medicine specialists who want to expand their knowledge and skills beyond their own discipline. It is also the main French language international medium for French research works. The journal publishes each month editorials, original articles, review articles, short communications, etc. These articles address the fundamental and innumerable facets of internal medicine, spanning all medical specialties. Manuscripts may be submitted in French or in English. La revue de medecine interne also includes additional issues publishing the proceedings of the two annual French meetings of internal medicine (June and December), as well as thematic issues.
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