Intermittent Hypoxia as a Model of Obstructive Sleep Apnea

IF 4.9 Q2 CLINICAL NEUROLOGY Sleep Medicine Clinics Pub Date : 2025-03-01 Epub Date: 2024-11-16 DOI:10.1016/j.jsmc.2024.10.009
Mohammad Badran B Pharm, MSc, PhD , David Gozal MD, MBA, PhD (Hon)
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间歇性缺氧作为阻塞性睡眠呼吸暂停的一种模式:现在和未来。
间歇性缺氧(IH)是一种非常常见的疾病,其特征是反复发作的低氧水平穿插于正常缺氧期,常见于阻塞性睡眠呼吸暂停(OSA)和肺部疾病。在OSA患者中,IH的发生是由于睡眠期间周期性气道阻塞,导致血氧饱和度短暂下降,随后再氧合。未来的方向包括标准化IH方案,将患者的可变性纳入所管理的IH档案,并利用战略开发的动物模型来提高IH相关研究的可靠性和适用性。
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来源期刊
Sleep Medicine Clinics
Sleep Medicine Clinics CLINICAL NEUROLOGY-
CiteScore
6.00
自引率
3.60%
发文量
79
期刊介绍: Sleep Medicine Clinics provides a forum for invited, topical reviews in this rapidly growing field. Each issue, guest edited by a leader in the field of Sleep Medicine, provides expert, state-of-the-art reviews on a single topic, making ample use of figures, diagrams, and tables. Topics such as Obstructive Sleep Apnea, Insomnia, and Parasomnias are presented clearly and comprehensively in the Sleep Medicine Clinics?perfect for any clinician who works with patients suffering from sleep disorders.
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