Mariia V. Melnik, Vladimir N. Mikhaylov, Alexander S. Novikov, Mikhail A. Kinzhalov, Alexander S. Bunev, Mariya A. Kryukova, Viktor N. Sorokoumov and Irina A. Balova*,
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引用次数: 0
Abstract
This study presents the synthesis of N-alkynylated acyclic diaminocarbene (ADC) complexes of palladium(II) and platinum(II) and their intramolecular cyclization via trans-chlorometalation. The reactions of propargylamines with bis-isocyanide complexes of Pd(II) and Pt(II) produced the desired ADC complexes in good yields. The NH,NH-diaminocarbene complexes were unstable in solution and underwent intramolecular cyclization into chlorometalated products. These findings provide a novel route to stable N-alkynylated ADC complexes with potential applications in catalysis and medicinal chemistry. The complexes synthesized exhibit promising structural and reactive properties suitable for further exploration.
本文研究了钯（II）和铂（II） n -炔基化无环二氨基（ADC）配合物的合成及其通过反氯金属化的分子内环化。丙胺与Pd（II）和Pt（II）的双异氰化物配合物反应，产率高，得到所需的ADC配合物。NH、NH-二氨基羰基配合物在溶液中不稳定，并发生分子内环化生成氯金属化产物。这些发现为制备稳定的n -炔基化ADC复合物提供了一条新的途径，在催化和药物化学方面具有潜在的应用前景。合成的配合物具有良好的结构和活性，值得进一步研究。
期刊介绍：
Organometallics is the flagship journal of organometallic chemistry and records progress in one of the most active fields of science, bridging organic and inorganic chemistry. The journal publishes Articles, Communications, Reviews, and Tutorials (instructional overviews) that depict research on the synthesis, structure, bonding, chemical reactivity, and reaction mechanisms for a variety of applications, including catalyst design and catalytic processes; main-group, transition-metal, and lanthanide and actinide metal chemistry; synthetic aspects of polymer science and materials science; and bioorganometallic chemistry.
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