An atypical case of infective endocarditis initially diagnosed as myopericarditis

JEM reports Pub Date : 2025-03-01 Epub Date: 2025-01-27 DOI:10.1016/j.jemrpt.2025.100145
Negin Ceraolo , Rachel Dietz , Spencer Prete , Erin L Simon
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Abstract

Background

Acute myopericarditis is inflammation of the pericardium, or the membrane surrounding the heart, and the myocardium, or the muscular myocardial layer of the heart. Infective endocarditis is an infection of the cardiac endothelium. Diagnosis relies on clinical evaluation, blood cultures to identify the causative organism, and echocardiography to visualize vegetations on heart valves. In the emergency department (ED), distinguishing between myopericarditis and infective endocarditis is crucial to avoid misdiagnosis.

Case report

We present the case of a 36-year-old male who was initially hospitalized for myocarditis and discharged on medications with cardiology follow-up planned. Twelve days later, the patient was readmitted with recurring chest pain. A bedside cardiac ultrasound showed mild mitral regurgitation. The patient was found to have bacteremia with Streptococcus anginosus which was concerning for endocarditis. The patient was transferred to a quaternary care hospital, where he underwent successful mitral valve repair.

Why should an emergency physician be aware of this?

In the ED setting, it is crucial to broaden differential diagnoses. Myopericarditis can sometimes result from endocarditis, which can present in various ways. Therefore, endocarditis should be ruled out in acute presentations of chest pain. To avoid missing cases of endocarditis, obtaining blood cultures from patients with myopericarditis symptoms is essential. Additionally, expediting a transesophageal echocardiogram (TEE) can lead to a faster and more accurate diagnosis. Promptly conducting these tests can reduce the number of missed endocarditis cases and prevent patients from returning to the emergency department.
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一例不典型的感染性心内膜炎,最初诊断为心包炎
背景:急性心肌炎是心包(即包围心脏的膜)和心肌(即心脏的心肌肌层)的炎症。感染性心内膜炎是一种心脏内皮的感染。诊断依赖于临床评估,血培养来确定致病生物,超声心动图来观察心脏瓣膜上的植被。在急诊科(ED),区分心包炎和感染性心内膜炎是避免误诊的关键。病例报告我们报告一位36岁男性患者,他最初因心肌炎住院,出院后接受药物治疗,并计划进行心脏病学随访。12天后,患者再次因胸痛复发入院。床边心脏超声显示轻度二尖瓣返流。患者被发现有血管链球菌菌血症,可能引起心内膜炎。患者被转移到一家第四护理医院,在那里他接受了成功的二尖瓣修复。急诊医生为什么要意识到这一点?在急诊科,扩大鉴别诊断是至关重要的。心包炎有时可由心内膜炎引起,其表现形式多种多样。因此,急性胸痛时应排除心内膜炎。为避免遗漏心内膜炎病例,有心肌炎症状的患者进行血培养是必要的。此外,加快经食管超声心动图(TEE)可以导致更快,更准确的诊断。及时进行这些检查可以减少心内膜炎漏诊病例的数量,并防止患者返回急诊室。
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来源期刊
JEM reports
JEM reports Emergency Medicine
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