Electrochemical Synthesis of Alkenylsulfonates from Alkynes, NaHSO3 and Alcohols

IF 5.5 1区 化学 Q2 CHEMISTRY, MULTIDISCIPLINARY Chinese Journal of Chemistry Pub Date : 2024-11-07 DOI:10.1002/cjoc.202400962
Xiaoman Wang, Qianqian Chen, Jinhang Zhou, Yi Hu, Shengqing Ye, Jie Wu
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Abstract

Alkenylsulfonates are commonly encountered in medicinal chemistry, polymer chemistry, and organic synthesis. In this research, an electrochemical reaction involving alkynes, NaHSO3, and alcohols has been developed. This method yields functionalized alkenylsulfonates in good yields with broad functional group tolerance. Mechanism studies indicate that anodic oxidation of inorganic sulfite, radical insertion process, and HAT process are involved in this transformation.

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由炔、NaHSO3和醇类电化学合成烯基磺酸盐
烯基磺酸盐在药物化学、聚合物化学和有机合成中很常见。在这项研究中,开发了一种涉及炔、NaHSO3和醇的电化学反应。该方法产率高、官能团耐受性广的功能化烯基磺酸盐。机理研究表明,无机亚硫酸盐的阳极氧化、自由基插入过程和HAT过程参与了这一转化过程。
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来源期刊
Chinese Journal of Chemistry
Chinese Journal of Chemistry 化学-化学综合
CiteScore
8.80
自引率
14.80%
发文量
422
审稿时长
1.7 months
期刊介绍: The Chinese Journal of Chemistry is an international forum for peer-reviewed original research results in all fields of chemistry. Founded in 1983 under the name Acta Chimica Sinica English Edition and renamed in 1990 as Chinese Journal of Chemistry, the journal publishes a stimulating mixture of Accounts, Full Papers, Notes and Communications in English.
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