Inside Front Cover: Volume 4 Issue 1

Abstract

Inside Front Cover: In the review of doi:10.1002/idm2.12214, the chemical strategies to improve the safety of organic/polymeric conjugated materials in biomedical applications are summarized and discussed. As depicted in the image, the precise designed materials would become metabolizable, or degradable by either endogenous reactive oxygen species or external stimuli, and subsequently excreted through liver or kidney. After disease diagnosis or treatment, such materials could be rapidly inactivated and subsequently excreted from the body, exhibiting high biological safety due to its efficient elimination, which highlight their scientific significance with biomedical and even clinical application values.