Alkylcyanation of Unactivated Alkenes with Protic C(sp3)−H Feedstocks via Radical-Initiated Intramolecular Cyano Group Migration Enabled by Photoredox/Brønsted Base Dual Catalysis
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引用次数: 0
Abstract
Cyanofunctionalization of alkenes via radical-initiated cyano migration was a straightforward pathway to access alkyl nitriles. Herein, By the synergistic merger of photoredox catalysis and Brønsted base catalysis, a mild protocol of alkylcyanation of unactivated alkenes with protic C(sp3)−H feedstocks via intramolecular 1,4-cyano group migration was reported. This method was enabled in an atom-, and step-economy manner, delivering a series of γ-cyanoester derivatives in moderate to excellent yields.
ChemPhotoChemChemistry-Physical and Theoretical Chemistry
CiteScore
5.80
自引率
5.40%
发文量
165
期刊介绍：
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