Yongqi Yu , Jinjin Bai , Mengdan You , Jiajia Yu , Wenguang Li , Yuanjiu Xiao , Shiyu Zhang , Zhenhua Xiong , Ze Tan
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引用次数: 0
Abstract
A highly simple and practical Cp∗Co(III)-catalyzed C–H amidation of 2-arylimidazo[1,2-α]pyridines was developed, during which dioxazolones were used as the amidating reagents. This method features excellent regioselectivity, operational simplicity, and good substrate compatibility, and various amidated 2-arylimidazoheterocycles were efficiently synthesized in 34–81 % yields. Furthermore, mechanistic studies reveal that the C–H bond cleavage may be involved in the turnover-limiting stage.
期刊介绍：
Tetrahedron publishes full accounts of research having outstanding significance in the broad field of organic chemistry and its related disciplines, such as organic materials and bio-organic chemistry.
Regular papers in Tetrahedron are expected to represent detailed accounts of an original study having substantially greater scope and details than that found in a communication, as published in Tetrahedron Letters.
Tetrahedron also publishes thematic collections of papers as special issues and ''Reports'', commissioned in-depth reviews providing a comprehensive overview of a research area.
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