Next-generation biopolymer gels: innovations in drug delivery and theranostics

IF 6.1 3区 医学 Q1 MATERIALS SCIENCE, BIOMATERIALS Journal of Materials Chemistry B Pub Date : 2025-01-22 DOI:10.1039/D4TB02068E
Danish Ahmad Shergujri, Murtaza Ahmad Khanday, Aisha Noor, Mohd Adnan, Iqra Arif, Syed Naiem Raza, Reyaz Hassan Mir and Nisar Ahmad Khan
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Abstract

Biopolymers or natural polymers like chitosan, cellulose, alginate, collagen, etc. have gained significant interest recently due to their remarkable tunable properties that make them appropriate for a variety of applications & play a crucial role in everyday life. The features of biopolymers which include biodegradability, biocompatibility, sustainability, affordability, & availability are vital for creating products for use in biomedical fields. Apart from these characteristics, smart or stimuli-responsive biopolymers also show a distinctive property of being susceptible to various factors like pH, temperature, light intensity, & electrical or magnetic fields. The current review would present a brief idea about smart biopolymer gels along with their biomedical applications. The use of smart biopolymers gels as theranostic agents are also discussed in the present review. This review also focuses on the application of biopolymers in the fields of drug delivery, cancer treatment, tissue engineering & wound healing. These areas demonstrate the development and utilization of different types of biopolymers in current biomedical applications.

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下一代生物聚合物凝胶:给药和治疗学的创新。
生物聚合物或天然聚合物,如壳聚糖、纤维素、海藻酸盐、胶原蛋白等,由于其显著的可调特性,使其适用于各种应用,在日常生活中发挥着至关重要的作用,最近引起了人们的极大兴趣。生物聚合物的特性包括生物可降解性、生物相容性、可持续性、可负担性和可用性,这对于创造用于生物医学领域的产品至关重要。除了这些特性外,智能或刺激响应型生物聚合物还显示出易受各种因素影响的独特特性,如pH值、温度、光强度、电场或磁场。本文将简要介绍智能生物聚合物凝胶及其生物医学应用。本文还讨论了智能生物聚合物凝胶作为治疗药物的应用。综述了生物聚合物在药物传递、肿瘤治疗、组织工程和伤口愈合等领域的应用。这些领域展示了不同类型的生物聚合物在当前生物医学应用中的开发和利用。
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来源期刊
Journal of Materials Chemistry B
Journal of Materials Chemistry B MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
11.50
自引率
4.30%
发文量
866
期刊介绍: Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive: Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices
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