ANATOMICAL AND FUNCTIONAL OUTCOMES OF HEAVY SILICONE OIL (OXANE HD AND DENSIRON 68) IN COMPLEX PRIMARY RHEGMATOGENOUS RETINAL DETACHMENT.

IF 2.1 2区 医学 Q2 OPHTHALMOLOGY Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-01 DOI:10.1097/IAE.0000000000004419
Serhat Ermis, Ece Ozal, Murat Karapapak, Omer Faruk Peker, Sadık Altan Ozal
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Abstract

Purpose: To evaluate the efficacy of heavy silicone oils as endotamponades in the repair of primary complex rhegmatogenous retinal detachment.

Methods: This retrospective, single-centre, nonrandomized study included 82 eyes of 82 patients with primary macular-off rhegmatogenous retinal detachment associated with inferior proliferative vitreoretinopathy. Each eye was treated with one of two heavy silicone oil tamponades: Oxane HD or Densiron 68. Study outcomes were primary and final success rates, final logarithm of the minimum angle of resolution gain, and postoperative complications. The final outcome was based on the 12-month follow-up.

Results: Of the 82 eyes, 45 were treated with Oxane HD and 37 with Densiron 68. There were no significant differences in demographic and clinical characteristics between the groups. The primary and final surgical success rates were 66.6% and 75.7% for Oxane HD and 75.6% and 81% for Densiron 68, respectively; these differences were not statistically significant. In addition, the final logarithm of the minimum angle of resolution gain was 0.36 ± 0.51 (median 0.2) in the Oxane HD group and 0.57 ± 0.58 (median 0.5) in the Densiron 68 group ( P = 0.027). Complication rates were similar between groups ( P > 0.05).

Conclusion: This study suggests that heavy silicone oils may be an effective alternative for suitable patients in primary complex rhegmatogenous retinal detachment cases, demonstrating high anatomical success and a low adverse event profile.

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重硅酮油(Oxane® HD 和 Densiron® 68)在复杂原发性流变性视网膜脱离中的解剖和功能效果。
目的:评价重质硅油(HSO)作为内压填塞剂修复原发性复杂孔源性视网膜脱离(RRD)的疗效。方法:这项回顾性、单中心、非随机研究纳入了82例伴有下网膜增生性玻璃体视网膜病变的原发性黄斑脱落性视网膜病变患者的82只眼。每只眼睛使用两种HSO填塞剂中的一种进行治疗:Oxane®HD或Densiron®68。研究结果包括最初和最终的成功率、最终logMAR增益和术后并发症。最终结果基于12个月的随访。结果:82只眼中,Oxane HD 45只眼,Densiron 68 37只眼。两组间的人口学和临床特征无显著差异。Oxane HD和Densiron 68的初、终手术成功率分别为66.6%和75.7%和75.6%和81%;这些差异没有统计学意义。此外,Oxane HD组的最终logMAR增益为0.36±0.51(中位0.2),Densiron 68组的最终logMAR增益为0.57±0.58(中位0.5)(p = 0.027)。两组并发症发生率相似(p < 0.05)。结论:我们的研究表明,hso可能是原发性复杂RRD病例中合适患者的有效替代方案,具有较高的解剖学成功率和较低的不良事件。
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来源期刊
CiteScore
5.70
自引率
9.10%
发文量
554
审稿时长
3-6 weeks
期刊介绍: ​RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.
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