Mortality From Infectious Pneumonia Associated With the Severity of Airflow Limitation in Pneumoconiosis: Proportional Mortality Study as a Case-Control Study.

IF 1.4 Journal of occupational and environmental medicine Pub Date : 2025-04-01 Epub Date: 2025-01-28 DOI:10.1097/JOM.0000000000003328

WonYang Kang, Daeho Kim, Mi-Yeon Kim, Subin Moon, YouLim Lee, Sungsook Lee, Byung-Soon Choi

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Abstract

Objective: The aim of this study was to investigate whether the mortality risk from infectious pneumonia was associated with the severity of airflow limitation among subjects in the cohort of pneumoconiosis.

Methods: Proportional mortality study was designed as a case-control study with 347 cases and 328 controls. Mortality odds ratios (ORs) were evaluated according to the severity of airflow limitation.

Results: The odds of mortality from pneumonia among the severe and very severe airflow limitation groups who performed spirometry at the time less than 1 year ago before death were 2.34 (OR 2.34; 95% confidence interval 1.04 to 5.28) and 8.77 times (OR 8.77; 95% confidence interval 1.69 to 45.68) greater compared to the nonairflow limitation group.

Conclusions: Severe airflow limitation in pneumoconiosis increases mortality from infectious pneumonia, presenting a dose-response relationship.

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尘肺中与气流受限严重程度相关的感染性肺炎死亡率：作为病例对照研究的比例死亡率研究

摘要：目的：探讨尘肺队列中感染性肺炎死亡风险是否与气流受限严重程度相关。方法：比例死亡率研究采用病例-对照研究，病例347例，对照组328例。根据气流限制的严重程度评估死亡率优势比（OR）。结果：严重和极严重气流受限组在死亡前1年内进行肺活量测定的肺炎死亡率为2.34 (OR 2.34；95% CI 1.04 ~ 5.28)和8.77倍(OR 8.77；95% CI（1.69 ~ 45.68）高于无气流限制组。结论：尘肺严重气流受限会增加感染性肺炎的死亡率，并呈现剂量-反应关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of occupational and environmental medicine

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