Alma Sophia Barisaac, Enas R. Abu-Zhayia, Nabieh Ayoub
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引用次数: 0
Abstract
Metabolite microenvironment shapes cancer treatment strategies. In a recent paper in Nature, Jin et al.1 demonstrate that valine deprivation triggers HDAC6 entry into the nucleus, leading to accumulation of DNA damage that could be harnessed for targeted cancer therapy.
期刊介绍：
Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.
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