NAVT-net neuron attention visual taylor network for lung cancer detection using CT images

IF 3.1 4区 生物学 Q2 BIOLOGY Computational Biology and Chemistry Pub Date : 2025-01-25 DOI:10.1016/j.compbiolchem.2025.108363
Lokanathan Jimson , John Patrick Ananth
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Abstract

Lung Cancer is regarded as a common fatal disease affecting humans throughout the entire world. Early diagnosis is vital to save the patient’s life and Computed Tomography (CT) scans are referred to as the major imaging modes but, the manual examination of a CT scan is time-consuming and results in errors. Hence, a novel system of Neuron Attention Visual Taylor Network (NAVT-Net) is developed to detect lung cancer. At first, the CT image is acquired, and then, the input image is filtered based on homomorphic filtering. Then, the lung nodule is segmented using the Dual-Branch-UNet (DB-UNet). Later, the image augmentation is achieved by resizing, flipping, as well as rotation. Next, the shape-based features are extracted and subjected to the last stage of lung cancer detection, which is done by the NAVT-Net system that is established on the basis of Neuron Attention Stage-by-Stage Network (NASNet), Visual Geometry Group-16 (VGG16), and Taylor series. Hence, the experimental results of the developed NAVT-Net system achieved high values of 92.176 % accuracy, 93.997 % of True Positive Rate (TPR), 92.189 % of True Negative Rate (TNR), F1-score of 90.999 %, and precision of 91.998 %, computational time, and memory usage of 37.879 s, and 41.100MB at K-values of 9.
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nvt -net神经元关注视觉泰勒网络用于肺癌CT图像检测
肺癌被认为是影响全世界人类的常见致命疾病。早期诊断对于挽救患者的生命至关重要,计算机断层扫描(CT)被认为是主要的成像模式,但人工检查CT扫描既耗时又容易出错。因此,我们开发了一种新的神经元注意视觉泰勒网络(NAVT-Net)系统来检测肺癌。首先对CT图像进行采集,然后对输入图像进行同态滤波。然后,使用双分支unet (DB-UNet)对肺结节进行分割。然后,通过调整大小、翻转和旋转来实现图像增强。接下来,提取基于形状的特征并进行最后阶段的肺癌检测,这是由基于神经元注意阶段网络(neural Attention stage -by- stage Network, NASNet)、视觉几何组-16 (Visual Geometry Group-16)和泰勒级数建立的NAVT-Net系统完成的。因此,所开发的NAVT-Net系统在k值为9时,准确率为92.176 %,真阳性率(TPR)为93.997 %,真阴性率(TNR)为92.189 %,f1评分为90.999 %,准确率为91.998 %,计算时间和内存使用分别为37.879 s和41.100MB。
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来源期刊
Computational Biology and Chemistry
Computational Biology and Chemistry 生物-计算机:跨学科应用
CiteScore
6.10
自引率
3.20%
发文量
142
审稿时长
24 days
期刊介绍: Computational Biology and Chemistry publishes original research papers and review articles in all areas of computational life sciences. High quality research contributions with a major computational component in the areas of nucleic acid and protein sequence research, molecular evolution, molecular genetics (functional genomics and proteomics), theory and practice of either biology-specific or chemical-biology-specific modeling, and structural biology of nucleic acids and proteins are particularly welcome. Exceptionally high quality research work in bioinformatics, systems biology, ecology, computational pharmacology, metabolism, biomedical engineering, epidemiology, and statistical genetics will also be considered. Given their inherent uncertainty, protein modeling and molecular docking studies should be thoroughly validated. In the absence of experimental results for validation, the use of molecular dynamics simulations along with detailed free energy calculations, for example, should be used as complementary techniques to support the major conclusions. Submissions of premature modeling exercises without additional biological insights will not be considered. Review articles will generally be commissioned by the editors and should not be submitted to the journal without explicit invitation. However prospective authors are welcome to send a brief (one to three pages) synopsis, which will be evaluated by the editors.
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