Deciphering the impact of microRNAs in plant biology: a review of computational insights and experimental validation.

IF 2.8 4区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Biology Reports Pub Date : 2025-02-06 DOI:10.1007/s11033-025-10273-0
Tamilarasi Palani, Divya Selvakumar, Bharathi Nathan, Varanavasiappan Shanmugam, Kavithamani Duraisamy, Jayakanthan Mannu
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Abstract

Exploring the complex world of microRNA (miRNA) biogenesis and functions in plants is essential for understanding their diverse regulatory mechanisms. This review highlights the processes involved in miRNA biogenesis and their crucial roles in growth and development of plant, stress responses, and nutrient homeostasis. miRNAs play a central role in various developmental processes, including the transition from the juvenile to adult stage, the growth of shoot apical meristem, leaf and floral morphogenesis, and the determination of flowering time. By presenting the current state of research, we focus on the vital role of computational tools and databases in deciphering the regulatory networks controlled by miRNAs, which helps us navigate the intricate world of plant biology. Furthermore, it stresses the importance of experimental validation techniques in confirming computational predictions, ensuring that miRNA research is reliable and robust. As the field continues to grow, this review emphasizes the urgent need for integrated approaches, to deepen our knowledge of plant miRNA biology and its implications. These insights will pave the way for advancements in crop improvement, stress resilience, and biotechnological innovations.

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破译microrna在植物生物学中的影响:计算见解和实验验证的回顾。
探索植物中microRNA (miRNA)生物发生和功能的复杂世界对于理解其多样的调控机制至关重要。本文综述了miRNA的生物发生过程及其在植物生长发育、逆境响应和营养平衡中的重要作用。mirna在植物幼体向成体的转变、茎尖分生组织的生长、叶和花的形态发生以及开花时间的决定等发育过程中发挥着核心作用。通过介绍目前的研究状况,我们关注计算工具和数据库在破译mirna控制的调控网络中的重要作用,这有助于我们导航复杂的植物生物学世界。此外,它强调了实验验证技术在确认计算预测方面的重要性,确保miRNA研究的可靠性和鲁棒性。随着该领域的不断发展,本综述强调迫切需要综合方法,以加深我们对植物miRNA生物学及其意义的了解。这些见解将为作物改良、抗逆性和生物技术创新的进步铺平道路。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Molecular Biology Reports
Molecular Biology Reports 生物-生化与分子生物学
CiteScore
5.00
自引率
0.00%
发文量
1048
审稿时长
5.6 months
期刊介绍: Molecular Biology Reports publishes original research papers and review articles that demonstrate novel molecular and cellular findings in both eukaryotes (animals, plants, algae, funghi) and prokaryotes (bacteria and archaea).The journal publishes results of both fundamental and translational research as well as new techniques that advance experimental progress in the field and presents original research papers, short communications and (mini-) reviews.
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