Iron-catalyzed one-pot tandem oxidation/acylation/dearomatization of biaryl ynones with benzyl alcohols: access to diversified acylated spiro[5.5]trienones
Dong Xia , Yanfeng Miao , Hongjian Ji , Wenchao Yang , Yun Shi
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引用次数: 0
Abstract
A new iron-catalyzed tandem cyclization and 6-exo-trig dearomatization reaction of biaryl ynones with readily available benzyl alcohols was developed. In the presence of Fe(acac)3 and tert-butyl hydroperoxide,a variety of acylated spiro[5.5]trienones were prepared through cascade oxidation/acylation/dearomatization process using benzyl alcohols as acylation reagent.
期刊介绍：
Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.
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