Carbon Dots: Emerging Nanomaterials for Ovarian Cancer Diagnosis and Therapy.

IF 2.5 4区 医学 Q2 PHARMACOLOGY & PHARMACY Current drug targets Pub Date : 2026-01-01 DOI:10.2174/0113894501347816241223065618
V Anoop Narayanan, Rajesh B R D Yamajala, Jayachandran Venkatesan, Myung-Geol Pang, Gangaraju Gedda
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Abstract

Delayed diagnosis and limited treatment options make ovarian cancer difficult to treat. This paper examines the growing role of Carbon Dots (CDs) in ovarian cancer diagnosis and treatment. Photoluminescence and biocompatibility make CDs ideal for biomedical use. We emphasize their ability to improve fluorescence and molecular imaging in radiology and diagnostics. We also demonstrate the efficacy of carbon dots in targeted drug delivery systems in overcoming drug resistance and improving therapeutic outcomes. Photodynamic and photothermal therapies are used to show that CDs can treat hypoxic ovarian cancer tumours. We also discuss CD safety issues and constraints, emphasising the need for thorough assessments and fine-tuning. Future research focuses on personalised medicine and CD integration with other therapies. This text concludes by discussing CDs' clinical use and the challenges of production and regulatory approval. CDs can improve ovarian cancer diagnosis and treatment, improving patient outcomes and survival.

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新型碳点纳米材料用于卵巢癌的诊断和治疗。
延迟诊断和有限的治疗选择使卵巢癌难以治疗。本文探讨了碳点(cd)在卵巢癌诊断和治疗中的日益重要的作用。光致发光和生物相容性使cd成为生物医学用途的理想选择。我们强调他们在成像和诊断中提高荧光和分子成像的能力。我们还证明了碳点在靶向药物递送系统中克服耐药性和改善治疗结果的功效。光动力和光热疗法被用来证明CDs可以治疗缺氧卵巢癌肿瘤。我们还讨论了CD安全问题和限制,强调需要进行彻底的评估和微调。未来的研究重点是个性化医疗和乳糜泻与其他疗法的结合。本文最后讨论了cd的临床应用以及生产和监管批准的挑战。cd可以改善卵巢癌的诊断和治疗,改善患者的预后和生存率。
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来源期刊
Current drug targets
Current drug targets 医学-药学
CiteScore
6.20
自引率
0.00%
发文量
127
审稿时长
3-8 weeks
期刊介绍: Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication mini- & full-length review articles and drug clinical trial studies. As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.
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