{"title":"mSphere of Influence: Complement activity beyond systemic circulation-implications in the context of infections.","authors":"Jigar V Desai","doi":"10.1128/msphere.00531-24","DOIUrl":null,"url":null,"abstract":"<p><p>Jigar V. Desai works in the field of immunology, studying the mucosal and systemic complement systems and their roles in regulating the immune response. In this mSphere of Influence article, he reflects on how the papers by the Kemper, Kulkarni, and Kasper laboratories made an impact on his ongoing work investigating the cell-intrinsic and extrinsic regulation of complement and studying its impacts on mucosal and systemic immunity.</p>","PeriodicalId":19052,"journal":{"name":"mSphere","volume":" ","pages":"e0053124"},"PeriodicalIF":3.7000,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"mSphere","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1128/msphere.00531-24","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Jigar V. Desai works in the field of immunology, studying the mucosal and systemic complement systems and their roles in regulating the immune response. In this mSphere of Influence article, he reflects on how the papers by the Kemper, Kulkarni, and Kasper laboratories made an impact on his ongoing work investigating the cell-intrinsic and extrinsic regulation of complement and studying its impacts on mucosal and systemic immunity.
期刊介绍：
mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.
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