Effect of osteopathic manipulative treatment on pain in palliative care patients: a randomized placebo-controlled clinical trial.

IF 3.4 Q2 NEUROSCIENCES Pain Reports Pub Date : 2025-02-05 eCollection Date: 2025-04-01 DOI:10.1097/PR9.0000000000001239
Yann Galeazzi, Nicolas Houel, Léa Gouaux, Anne Rohan, Hélène Le Heiget, Camille Jung, Bruno Housset, Laurent Stubbe
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引用次数: 0

Abstract

Introduction: Standard osteopathic manipulative therapy (OMT) is used as a supportive care for pain management in cancer patients.

Objectives: The present study aimed to compare the efficacy of OMT with that of a sham treatment to attenuate pain in cancer patients in a palliative care unit.

Methods: This randomized clinical trial was a simple blind, monocentric, placebo-controlled study. Seventy-five patients were randomly distributed between standard and sham OMT sessions at a 1:1 ratio, receiving standard or sham treatment every 2 days for the 7 days of the study. Patients were assessed using a self-administered visual analog scale (VAS)-ranging from 0 to 100, recorded in the morning and evening. They also completed the QLQ-C15-PAL quality-of-life questionnaire on the first and last day of the study. For participants with controlled analgesia pumps, the number of analgesic doses was recorded.

Results: The OMT group demonstrated a significant effect of days, circadian period, and group on VAS pain decrease (P < 0.05). The VAS pain score for the OMT group exhibited a notable decline from the third day (D3 pm) (P = 0.03) to D6 pm (P = 1.28 × 10-05) with 43.2% improvement by the conclusion of the study. On D6, the quality-of-life score exhibited a tendency towards improvement. Patients with analgesia pumps showed a 31.58% reduction in their demand for analgesics (P = 0.016). No significant results were observed between D0 and D3.

Conclusion: It is hypothesized that OMT could prove an efficacious method of pain management in cancer patients receiving palliative care, in addition to conventional cancer treatment.

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来源期刊
Pain Reports
Pain Reports Medicine-Anesthesiology and Pain Medicine
CiteScore
7.50
自引率
2.10%
发文量
93
审稿时长
8 weeks
期刊最新文献
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