Anatomic healing of greater tuberosity improves range of motion and functional outcomes after reverse total shoulder arthroplasty for proximal humerus fractures: an updated systematic review and meta-analysis on 21 studies

IF 2.9 2区 医学 Q1 ORTHOPEDICS Journal of Shoulder and Elbow Surgery Pub Date : 2025-02-04 DOI:10.1016/j.jse.2024.12.028
Calogero Di Naro MD , Giuseppe Gianluca Costa MD , Gianluca Zocco MD , Mirko Sicurella MD , Gianluca Testa PhD , Vito Pavone PhD , Umile Giuseppe Longo PhD , Rocco Papalia PhD , Arcangelo Russo PhD
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Abstract

Background

Reverse shoulder arthroplasty (rTSA) is increasingly being used to treat complex proximal humerus fractures, especially in the senior population. The question of whether it is worthwhile to repair the greater tuberosity (GT) after rTSA for proximal humerus fractures still needs to be answered.

Methods

A systematic review was performed on PubMed, Scopus, Cochrane library, and Embase for studies available up to February 2024 focused on tuberosity repair after rTSA for proximal humerus fracture and reporting clinical outcomes and range of motion (ROM) between patients with anatomic GT healing and patients with malunion or nonunion of GT. The primary outcome was the rate of anatomically healed GTs. Patients with GT malunion or nonunion were collectively categorized as nonhealed. The secondary outcomes were active ROM and functional scores. A random-effects proportion meta-analysis (weighted for individual study size) was generated for calculation of the pooled rate of GT nonhealing. The plausible predictive factors for GT nonhealing (gender distribution, mean age, mean time from injury to surgery, dominant side distribution, and humeral inclination of the implanted prostheses) were analyzed by performing a metaregression. Any statistically significant difference in terms of ROM (active anterior elevation, abduction, and external rotation) between healed and nonhealed GT groups was detected by constructing individual forest plots.

Results

A total of 21 studies were selected and included in the meta-analysis, with a sample of 1616 rTSAs in 1614 patients. The rate of GT nonhealing ranged from 15.0% to 63.2%, with a pooled rate of 31.9% (95% confidence interval, 25.6%-38.2%; I2 = 86.8%). The metaregression failed to individuate any plausible predictive factor among the evaluated elements. Anatomic GT healing provided improved ROM in active abduction (P = .002), anterior elevation (P < .00001), and external rotation (P < .0001). With regard to internal rotation, a statistically significant difference in favor of the GT healed group was reported in only 3 of 13 studies. Similarly, the random-effects meta-analysis demonstrated better functional scores in patients with healed GT according to 3 of 5 functional scores.

Conclusion

GT healing after rTSA for proximal humerus fracture provides increased ROM and better functional outcomes. Moreover, this does not result in a higher level of pain for patients. Future prospective studies with more rigorous selection criteria are welcome to increase the level of evidence on this topic.
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大结节解剖愈合改善肱骨近端骨折反向全肩关节置换术后的活动范围和功能结果。对21项研究的最新系统综述和荟萃分析。
背景:反向肩关节置换术(rTSA)越来越多地被用于治疗复杂的肱骨近端骨折,特别是在老年人中。肱骨近端骨折rTSA后是否值得修复大结节(GT)的问题仍然需要回答。方法:系统回顾PubMed、Scopus、Cochrane文库和EMBASE上截至2024年2月的关于肱骨近端骨折rTSA后结节修复的研究,并报告解剖性GT愈合患者与GT畸形愈合或不愈合患者的临床结果和活动范围(ROM)。主要结果是解剖性GT愈合率。GT畸形愈合或不愈合的患者统称为未愈合。次要结果是活动性ROM和功能评分。随机效应比例荟萃分析(按个体研究规模加权)用于计算GT不愈合的总发生率。通过meta回归分析GT不愈合的可能预测因素(性别分布、平均年龄、从受伤到手术的平均时间、优势侧分布、植入假体的肱骨倾角)。通过构建单独的森林样地来检测愈合组和未愈合组之间ROM(主动前向上、外展和外旋)的统计学差异。结果:共有21项研究被纳入meta分析,1614例患者的1616例rTSAs样本。GT不愈合率为15.0% ~ 63.2%,合并率为31.9% (95% CI, 25.6% ~ 38.2%;I2 = 86.8%)。元回归未能在被评估的因素中单独确定任何似是而非的预测因素。解剖性GT愈合可改善主动外展(p=0.002)和前凸(p)的ROM。结论:肱骨近端骨折rTSA后GT愈合可增加ROM和改善功能预后。此外,这不会导致患者更高程度的疼痛。欢迎未来有更严格选择标准的前瞻性研究来增加这一主题的证据水平。
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来源期刊
CiteScore
6.50
自引率
23.30%
发文量
604
审稿时长
11.2 weeks
期刊介绍: The official publication for eight leading specialty organizations, this authoritative journal is the only publication to focus exclusively on medical, surgical, and physical techniques for treating injury/disease of the upper extremity, including the shoulder girdle, arm, and elbow. Clinically oriented and peer-reviewed, the Journal provides an international forum for the exchange of information on new techniques, instruments, and materials. Journal of Shoulder and Elbow Surgery features vivid photos, professional illustrations, and explicit diagrams that demonstrate surgical approaches and depict implant devices. Topics covered include fractures, dislocations, diseases and injuries of the rotator cuff, imaging techniques, arthritis, arthroscopy, arthroplasty, and rehabilitation.
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