Under-five mortality and its associated factors in sub-Saharan Africa: a multilevel analysis of recent demographic and health surveys data based on Bayesian approach.

IF 2 3区 医学 Q2 PEDIATRICS BMC Pediatrics Pub Date : 2025-02-08 DOI:10.1186/s12887-025-05454-6
Atalay Liknaw Birhanie, Zemenu Tadesse Tessema, Bekalu Endalew, Koku Sisay Tamirat
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Abstract

Background: An estimated 75.8 under-five deaths per 1000 live births occurred in sub-Saharan Africa. This study aimed to investigate the prevalence and factors associated with under-five mortality in Sub-Saharan Africa.

Methods: This study was based on secondary data sources from 33 Sub-Saharan countries' recent Demography and Health surveys from 2010 to 2020. A weighted sample of 360,397 under-five children was included in the study. Bayesian multilevel binary logistic regression was fitted using the brms R package. Besides, leave one out information criteria was used for model comparison. The adjusted odds ratio (AOR) and its 95% credible interval (CrI) were reported for significant factors associated with under-five mortality.

Clinical trial number: not applicable.

Results: The prevalence of under-five mortality in sub Saharan Africa was 62 per 1000 live births (95%CI (56.29, 68.29). In sub region of SSA, it was 65 in central, 52 in eastern, 50 in southern and 73 in western region per 1000 live births. Multiple birth (AOR = 5.27; 95%CrI: 4.72, 5.87), number of under-five children 3 to 5 (AOR = 3.31; 95%CrI: 3.01, 3.60), caesarean section delivery (AOR = 1.64; 95%CrI: 1.47, 1.83), being unmarried (AOR = 1.16; 95%CrI 1.08, 1.26), using unimproved toilet (AOR = 1.08;95%CrI: 1.02, 1.16), birth order of 4th to 6th (AOR = 1.18; 95%CrI:1.1, 1.25),were risk factors of under-five mortality. Whereas, being female (AOR = 0.86; 95%CrI: 0.82, 0.91), preceding birth interval of 24-35 months (AOR = 0.61; 95%CrI: 0.57, 0.65) and above 36 months (AOR = 0.48; 95%CrI: 0.43, 0.49), ANC visit (AOR = 0.80; 95%CrI: 0.74 0.86), contraceptive use (AOR = 0.57; 95%CrI: 0.53, 0.61), were preventive factors of under-five mortality.

Conclusion: Under-five mortality remains the highest in sub-Saharan Africa. Most of the risk factors of under-five mortality were found to be preventable. Policymakers and other stakeholders should enhance maternal education, lengthen birth interval, ANC visit, improved toilet facilities and, giving special attention to small size child and cesarean section delivery to reduce under-five mortality.

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撒哈拉以南非洲五岁以下儿童死亡率及其相关因素:基于贝叶斯方法对最近人口和健康调查数据的多层次分析。
背景:撒哈拉以南非洲每1000例活产中估计有75.8例五岁以下儿童死亡。本研究旨在调查撒哈拉以南非洲五岁以下儿童死亡率的流行情况和相关因素。方法:本研究基于来自33个撒哈拉以南国家最近的2010年至2020年人口与健康调查的二手数据来源。该研究纳入了360397名5岁以下儿童的加权样本。采用brms R包拟合贝叶斯多水平二元逻辑回归。并采用留一信息准则进行模型比较。报告了与5岁以下儿童死亡率相关的重要因素的校正优势比(AOR)及其95%可信区间(CrI)。临床试验号:不适用。结果:撒哈拉以南非洲地区5岁以下儿童死亡率为62 / 1000活产(95%CI(56.29, 68.29))。在撒哈拉以南非洲次区域,每1000名活产婴儿中,中部为65人,东部为52人,南部为50人,西部为73人。多胞胎(AOR = 5.27;95%CrI: 4.72, 5.87), 5岁以下儿童数3 ~ 5 (AOR = 3.31;95%CrI: 3.01, 3.60),剖宫产(AOR = 1.64;95%CrI: 1.47, 1.83),未婚(AOR = 1.16;95%CrI = 1.08, 1.26),使用未改良厕所(AOR = 1.08;95%CrI: 1.02, 1.16),出生顺序4 ~ 6 (AOR = 1.18;95%CrI:1.1, 1.25)是5岁以下儿童死亡的危险因素。而女性(AOR = 0.86;95%CrI: 0.82, 0.91),产前间隔24-35个月(AOR = 0.61;95%CrI: 0.57, 0.65)及以上36个月(AOR = 0.48;95%CrI: 0.43, 0.49), ANC访视(AOR = 0.80;95%CrI: 0.74 0.86),避孕措施使用(AOR = 0.57;95%CrI: 0.53, 0.61)为5岁以下儿童死亡的预防因素。结论:五岁以下儿童死亡率在撒哈拉以南非洲仍然最高。5岁以下儿童死亡的大多数危险因素是可以预防的。决策者和其他利益攸关方应加强孕产妇教育,延长分娩间隔,进行产前检查,改善厕所设施,并特别关注小个子儿童和剖宫产分娩,以降低五岁以下儿童死亡率。
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来源期刊
BMC Pediatrics
BMC Pediatrics PEDIATRICS-
CiteScore
3.70
自引率
4.20%
发文量
683
审稿时长
3-8 weeks
期刊介绍: BMC Pediatrics is an open access journal publishing peer-reviewed research articles in all aspects of health care in neonates, children and adolescents, as well as related molecular genetics, pathophysiology, and epidemiology.
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