A Rare Case of Bullous Melanoma With Subepidermal Separation

Abstract

Several rare subtypes of melanoma, beyond the classic variants, have been described in the literature. The rarity of these variants can hinder recognition and lead to delays in clinical diagnosis. Bullous melanoma is one such rare subtype. Blister formation in bullous melanoma can occur either intraepidermally or subepidermally. While most reported cases exhibit intraepidermal separation, only three cases with subepidermal separation have been documented to date. Here, we present a rare case of bullous melanoma with subepidermal separation characterized by exceptional recurrent bullous episodes.