Pilot Study of Speech and Ventilation Quality of Life After Cleft Palate Repair in Chinese Patients

IF 2 3区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Laryngoscope Pub Date : 2025-02-08 DOI:10.1002/lary.32058
Hao Sui DDS, Weilong Liu PhD, Min Wu MD, Heng Yin MD, Meijun Du DDS, Jiali Chen DDS, Shiming Zhang DDS, Hanyao Huang PhD, Bing Shi PhD, Yong Lu PhD
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Abstract

Objective (s)

This pilot study aimed to assess the quality of life (QoL) in Chinese patients with velopharyngeal competence (VPC) after primary cleft palate surgery or after secondary posterior pharyngeal flap (PPF) surgery.

Methods

A two-center cross-sectional study was conducted in two stomatological hospitals in China between December 2021 and December 2022. A total of 68 patients and healthy volunteers were enrolled in this study, categorized into the control group, the group of patients with VPC after primary cleft palate repair, and the group of patients with VPC after secondary PPF. The Velopharyngeal Insufficiency (VPI) Effects on Life Outcomes (VELO) instrument and the Quebec Sleep Questionnaire (QSQ) were used for the assessment of speech-related QoL and ventilation-impairment-related QoL.

Results

Healthy subjects had better VELO total scores (speech-related QoL) than patients with VPC. Patients who reached VPC by secondary PPF surgery had better VELO scores in the domain of perception by others, compared with patients who reached VPC after the primary cleft palate surgery. Ventilation-impairment-related QoL assessment showed that patients who underwent secondary PPF surgery had worse QSQ total scores and domain scores than those who only had primary surgery. Surgical age only had a negative correlation with VELO scores of swallowing problems in patients who underwent PPF surgery.

Conclusions

Despite achieving VPC after both primary and secondary surgery, patients could still exhibit worse speech-related QoL than healthy individuals. Among patients with VPC, patients who underwent secondary PPF could have worse ventilation-impairment-related QoL than those who only had primary cleft palate surgery.

Level of Evidence

3 Laryngoscope, 135:2367–2374, 2025

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腭裂修复术后中国患者言语及呼吸生活质量的初步研究。
目的:本初步研究旨在评估中国腭裂术后腭咽功能正常(VPC)患者或继发性后咽瓣(PPF)术后的生活质量(QoL)。方法:于2021年12月至2022年12月在中国两家口腔医院进行双中心横断面研究。本研究共纳入68例患者和健康志愿者,分为对照组、原发性腭裂修复后VPC组和继发性PPF后VPC组。使用舌咽部功能不全(VPI)对生命结局的影响(VELO)量表和魁北克睡眠问卷(QSQ)评估言语相关的生活质量和呼吸障碍相关的生活质量。结果:健康受试者的VELO总分(言语相关生活质量)优于VPC患者。与初次腭裂术后达到VPC的患者相比,通过二次PPF手术达到VPC的患者在他人感知领域的VELO评分更高。与通气障碍相关的生活质量评估显示,接受二次PPF手术的患者的QSQ总分和领域评分低于仅接受一次手术的患者。手术年龄仅与PPF手术患者的吞咽问题VELO评分呈负相关。结论:尽管患者在一次和二次手术后都达到了VPC,但与健康个体相比,患者的语言相关生活质量仍然较差。在VPC患者中,接受继发性PPF的患者比只接受原发性腭裂手术的患者有更差的通气损伤相关生活质量。证据等级:3喉镜,2025。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Laryngoscope
Laryngoscope 医学-耳鼻喉科学
CiteScore
6.50
自引率
7.70%
发文量
500
审稿时长
2-4 weeks
期刊介绍: The Laryngoscope has been the leading source of information on advances in the diagnosis and treatment of head and neck disorders since 1890. The Laryngoscope is the first choice among otolaryngologists for publication of their important findings and techniques. Each monthly issue of The Laryngoscope features peer-reviewed medical, clinical, and research contributions in general otolaryngology, allergy/rhinology, otology/neurotology, laryngology/bronchoesophagology, head and neck surgery, sleep medicine, pediatric otolaryngology, facial plastics and reconstructive surgery, oncology, and communicative disorders. Contributions include papers and posters presented at the Annual and Section Meetings of the Triological Society, as well as independent papers, "How I Do It", "Triological Best Practice" articles, and contemporary reviews. Theses authored by the Triological Society’s new Fellows as well as papers presented at meetings of the American Laryngological Association are published in The Laryngoscope. • Broncho-esophagology • Communicative disorders • Head and neck surgery • Plastic and reconstructive facial surgery • Oncology • Speech and hearing defects
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