Treating Facial Scars using Polydioxanone Threads

IF 1.8 Q3 SURGERY JPRAS Open Pub Date : 2025-03-01 Epub Date: 2025-01-15 DOI:10.1016/j.jpra.2025.01.006
Mohammad Khaled Hamolaila, Mazen Zenati, Asaad Shehada
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Abstract

Traditional scar treatments, such as laser therapy, chemical peels, and surgery, are expensive and require long recovery times. Polydioxanone (PDO) threads offer a minimally invasive and cost-effective solution that enhances collagen production and skin texture.
This study aimed to evaluate the effectiveness of PDO threads in the management of atrophic facial scars due to the lack of clinical research on this topic.
A prospective clinical study was conducted on 20 patients with facial atrophic scars caused by accidents or previous surgical procedures. The patient and observer scar assessment scale was used to evaluate the scars from the observer's and patient's perspectives at three-time points for each patient. The observer assessment included the following variables: vascularity, pigmentation, thickness, pliability, surface area, and homogeneity. The patient assessment included the following variables: pain, color, stiffness, thickness, appearance, and itching.
Statistically significant improvement was observed in atrophic facial scars treated using PDO threads in all observer variables (p<0.001). Significant improvement was recorded in the patient's color, stiffness, thickness, and appearance variables; however, itching sensation increased between T0 and T1 with no statistically significant differences in the pain variable.
Within the limits of this study, we conclude that PDO threads are known for ease of use, availability, and biocompatibility. They biodegrade naturally, reducing irritation risk. By stimulating collagen, PDO threads promote natural skin regeneration and thereby improve scars without using foreign materials. The treatment method is safe and minimally invasive, with short recovery times. Clinical studies showed significant improvements in atrophic facial scars with high patient satisfaction.
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用聚二氧环酮线治疗面部疤痕
传统的疤痕治疗,如激光治疗、化学换肤和手术,都是昂贵的,需要很长的恢复时间。聚二氧环酮(PDO)丝线提供了一种微创和低成本的解决方案,可以增强胶原蛋白的产生和皮肤纹理。由于缺乏临床研究,本研究旨在评估PDO螺纹治疗萎缩性面部疤痕的有效性。对20例因意外事故或既往手术造成的面部萎缩性疤痕患者进行前瞻性临床研究。采用患者和观察者疤痕评估量表,分别从观察者和患者的角度在每个患者的三个时间点对疤痕进行评估。观察评估包括以下变量:血管性、色素沉着、厚度、柔韧性、表面积和均匀性。患者评估包括以下变量:疼痛、颜色、僵硬、厚度、外观和瘙痒。使用PDO线治疗萎缩性面部疤痕在所有观察变量中均有统计学显著改善(p<0.001)。患者的颜色、僵硬度、厚度和外观变量均有显著改善;然而,瘙痒感觉在T0和T1之间增加,疼痛变量没有统计学上的显着差异。在本研究的范围内,我们得出结论,PDO线程以易于使用,可用性和生物相容性而闻名。它们可以自然生物降解,降低刺激风险。通过刺激胶原蛋白,PDO线促进皮肤自然再生,从而改善疤痕,而不使用外来材料。该治疗方法安全、微创,恢复时间短。临床研究显示萎缩性面部疤痕有显著改善,患者满意度高。
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来源期刊
JPRAS Open
JPRAS Open Medicine-Surgery
CiteScore
1.60
自引率
0.00%
发文量
89
审稿时长
22 weeks
期刊介绍: JPRAS Open is an international, open access journal dedicated to publishing case reports, short communications, and full-length articles. JPRAS Open will provide the most current source of information and references in plastic, reconstructive & aesthetic surgery. The Journal is based on the continued need to improve surgical care by providing highlights in general reconstructive surgery; cleft lip, palate and craniofacial surgery; head and neck surgery; skin cancer; breast surgery; hand surgery; lower limb trauma; burns; and aesthetic surgery. The Journal will provide authors with fast publication times.
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