{"title":"Advanced genomic research in understanding fish-borne zoonotic parasitic infection","authors":"Sk Injamamul Islam , Piyanan Taweethavonsawat","doi":"10.1016/j.micpath.2025.107367","DOIUrl":null,"url":null,"abstract":"<div><div>Fish-borne zoonotic parasites pose substantial risks to human health and global aquaculture, primarily through raw or undercooked fish consumption. The rapid expansion of aquaculture, increasing global fish trade, and rising human populations have amplified these concerns. Despite widespread awareness of meat-borne zoonoses, fish-borne parasitic infections remain underrecognized, especially in developed countries. Traditional morphological and molecular methods have provided critical foundations for studying these parasites, yet recent genomic advances have revolutionized our understanding of their genetic diversity, biology, and host-pathogen dynamics. This review underscores the significance of integrating genomic approaches with conventional methods to enhance disease surveillance, risk assessment, and control strategies. Harnessing genomic tools will enable the development of effective interventions to mitigate zoonotic parasite impacts, protect human health, and promote sustainable aquaculture. A comprehensive, genomics-driven approach is essential to overcoming the global challenges of fish-borne zoonotic infections.</div></div>","PeriodicalId":18599,"journal":{"name":"Microbial pathogenesis","volume":"200 ","pages":"Article 107367"},"PeriodicalIF":3.3000,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microbial pathogenesis","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0882401025000920","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Fish-borne zoonotic parasites pose substantial risks to human health and global aquaculture, primarily through raw or undercooked fish consumption. The rapid expansion of aquaculture, increasing global fish trade, and rising human populations have amplified these concerns. Despite widespread awareness of meat-borne zoonoses, fish-borne parasitic infections remain underrecognized, especially in developed countries. Traditional morphological and molecular methods have provided critical foundations for studying these parasites, yet recent genomic advances have revolutionized our understanding of their genetic diversity, biology, and host-pathogen dynamics. This review underscores the significance of integrating genomic approaches with conventional methods to enhance disease surveillance, risk assessment, and control strategies. Harnessing genomic tools will enable the development of effective interventions to mitigate zoonotic parasite impacts, protect human health, and promote sustainable aquaculture. A comprehensive, genomics-driven approach is essential to overcoming the global challenges of fish-borne zoonotic infections.
期刊介绍:
Microbial Pathogenesis publishes original contributions and reviews about the molecular and cellular mechanisms of infectious diseases. It covers microbiology, host-pathogen interaction and immunology related to infectious agents, including bacteria, fungi, viruses and protozoa. It also accepts papers in the field of clinical microbiology, with the exception of case reports.
Research Areas Include:
-Pathogenesis
-Virulence factors
-Host susceptibility or resistance
-Immune mechanisms
-Identification, cloning and sequencing of relevant genes
-Genetic studies
-Viruses, prokaryotic organisms and protozoa
-Microbiota
-Systems biology related to infectious diseases
-Targets for vaccine design (pre-clinical studies)