Engineered Mesenchymal Stem Cell-Derived Extracellular Vesicles Scavenge Self-Antigens for Psoriasis Therapy via Modulating Metabolic and Immunological Disorders (Adv. Sci. 6/2025)

IF 14.1 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY Advanced Science Pub Date : 2025-02-10 DOI:10.1002/advs.202570031
Xin Zhou, Bo Tang, Qing Huang, Siyu Yang, Yang Jiang, Lizhou Xu, Wen Chen, Guangchang Shan, Xuankai Liao, Chongchao Hou, Zhihong Yao, Chaowei Zou, Rongying Ou, Yunsheng Xu, Danyang Li
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Abstract

Novel Therapy for Psoriasis

In article number 2410067, Xin Zhou, Yunsheng Xu, Danyang Li, and co-workers present a novel engineered mesenchymal stem cell-derived extracellular vesicles for treating psoriasis, a condition currently lacks a complete cure. This approach can effectively reduce psoriasis-specific self-antigens and modulate both metabolic and immunological disorders, thereby providing new insights for psoriasis therapy.

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工程间充质干细胞衍生的细胞外囊泡清除自身抗原通过调节代谢和免疫紊乱治疗银屑病(add . Sci. 6/2025)
小说治疗PsoriasisIn货号2410067,周鑫升(徐,丹阳,和同事提出一个新颖的设计间充质干细胞细胞外囊泡治疗牛皮癣,目前缺乏一个完整的治疗。该方法可以有效降低银屑病特异性自身抗原,调节代谢和免疫紊乱,从而为银屑病治疗提供新的见解。
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来源期刊
Advanced Science
Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY
CiteScore
18.90
自引率
2.60%
发文量
1602
审稿时长
1.9 months
期刊介绍: Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.
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