Naveenkumar Thoti, Deepika Gupta, Heera Lal, Indrapal Singh Aidhen
{"title":"Synthesis of 5-Aryltetrahydrobenzazepines","authors":"Naveenkumar Thoti, Deepika Gupta, Heera Lal, Indrapal Singh Aidhen","doi":"10.1002/jhet.4932","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Envisaging 5-aryltetrahydrobenzazepinone and 5-aryltetrahydrobenzazepines as conformationally locked potential B<sup>0</sup>AT1 inhibitors, a convenient synthetic route has been developed for their access. The synthetic route banks on using the Schmidt reaction for quick access to symmetrical/unsymmetrical 5-aryltetrahydrobenzazepinone and 5-aryltetrahydrobenzazepines.</p>\n </div>","PeriodicalId":194,"journal":{"name":"Journal of Heterocyclic Chemistry","volume":"62 2","pages":"219-239"},"PeriodicalIF":2.0000,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Heterocyclic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jhet.4932","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Envisaging 5-aryltetrahydrobenzazepinone and 5-aryltetrahydrobenzazepines as conformationally locked potential B0AT1 inhibitors, a convenient synthetic route has been developed for their access. The synthetic route banks on using the Schmidt reaction for quick access to symmetrical/unsymmetrical 5-aryltetrahydrobenzazepinone and 5-aryltetrahydrobenzazepines.
期刊介绍:
The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.