Frequency and pattern of dyslipidemia and its association with other risk factors among Type-2 Diabetics.

IF 1.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL Pakistan Journal of Medical Sciences Pub Date : 2025-02-01 DOI:10.12669/pjms.41.2.10264
Alia Ali Muhammad, Manal Afzaal, Mehak Joher Khan, Amena Moazzam Baig, Muhammad Aasim
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Abstract

Objective: To determine the frequency and pattern of dyslipidemia and its association with other risk factors among Type-2 diabetics.

Methods: This cross-sectional study was conducted in Diabetic Clinic of Shaikh Zayed Postgraduate Medical Institute Lahore from January-October 2023. Type-2 diabetics regardless of age were evaluated by fasting lipid profile and were further evaluated by BMI, HbA1c and smoking. Exclusion criteria was patients taking lipid lowering drugs and all other causes of secondary dyslipidemias other than diabetes. Data for normally distributed quantitative variables was presented by Mean±SD, and for skewed measures were presented by using median (IQR). Dyslipidemia was described for each trait by using frequency and percentages.

Results: A total of two hundred and twelve subjects were included in the study with the mean age of 53.4±9.1 years. About 96.6% patients were found to have different patterns of dyslipidemia that also showed positive association with smoking, uncontrolled HbA1c and obesity (p < 0.001).

Conclusion: There is very high prevalence of dyslipidemia among Type-2 diabetics especially those who are smokers, with poor glycemic control and overweight/obese. Early screening of patients for dyslipidemia with lifestyle modifications and treatment of dyslipidemia can reduce risk of CVD.

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2型糖尿病患者血脂异常的频率和模式及其与其他危险因素的关系
目的:了解2型糖尿病患者血脂异常的发生频率、类型及其与其他危险因素的关系。方法:本横断面研究于2023年1 - 10月在拉合尔谢赫扎耶德研究生医学院糖尿病门诊进行。2型糖尿病患者不论年龄均通过空腹血脂评估,并通过BMI、HbA1c和吸烟进一步评估。排除标准是服用降脂药物和除糖尿病以外所有其他继发性血脂异常的患者。正态分布的定量变量用Mean±SD表示,偏态的计量变量用中位数(IQR)表示。用频率和百分比描述各性状的血脂异常。结果:共纳入研究对象212例,平均年龄53.4±9.1岁。约96.6%的患者存在不同类型的血脂异常,且与吸烟、未控制的HbA1c和肥胖呈正相关(p < 0.001)。结论:2型糖尿病患者血脂异常发生率高,尤其是吸烟、血糖控制不良和超重/肥胖人群。早期筛查血脂异常患者并改变生活方式和治疗血脂异常可降低心血管疾病的风险。
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来源期刊
Pakistan Journal of Medical Sciences
Pakistan Journal of Medical Sciences 医学-医学:内科
CiteScore
4.10
自引率
9.10%
发文量
363
审稿时长
3-6 weeks
期刊介绍: It is a peer reviewed medical journal published regularly since 1984. It was previously known as quarterly "SPECIALIST" till December 31st 1999. It publishes original research articles, review articles, current practices, short communications & case reports. It attracts manuscripts not only from within Pakistan but also from over fifty countries from abroad. Copies of PJMS are sent to all the import medical libraries all over Pakistan and overseas particularly in South East Asia and Asia Pacific besides WHO EMRO Region countries. Eminent members of the medical profession at home and abroad regularly contribute their write-ups, manuscripts in our publications. We pursue an independent editorial policy, which allows an opportunity to the healthcare professionals to express their views without any fear or favour. That is why many opinion makers among the medical and pharmaceutical profession use this publication to communicate their viewpoint.
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