Cerebral palsy and perinatal mortality in children born in Norway to immigrant mothers

IF 4.3 2区 医学 Q1 CLINICAL NEUROLOGY Developmental Medicine and Child Neurology Pub Date : 2025-02-09 DOI:10.1111/dmcn.16271
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Abstract

This study aimed to compare the birth prevalence and clinical characteristics of cerebral palsy (CP) between children born to non-immigrant mothers and those born to immigrant mothers from high-income countries (HICs) and low- and middle-income countries (LMICs), as well as perinatal mortality rates. Data were collected from the Medical Birth Registry of Norway and the Norwegian Quality and Surveillance Registry for Cerebral Palsy, covering live births and perinatal deaths from 2000 to 2016.

Results showed that the prevalence of CP was higher among children of non-immigrant mothers, with a decreasing trend over time. Children of immigrant mothers from HICs had lower odds of CP, while those from LMICs also had lower odds despite higher rates of consanguinity and lower folate use during pregnancy. Perinatal mortality was higher among mothers from LMICs. Clinical characteristics of CP were similar across groups, but children from LMICs had a higher incidence of intellectual disabilities and brain grey matter injuries.

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挪威移民母亲所生儿童的脑瘫和围产期死亡率。
本研究旨在比较来自高收入国家(HICs)和低收入和中等收入国家(LMICs)的非移民母亲和移民母亲所生的儿童脑瘫(CP)的出生患病率和临床特征,以及围产期死亡率。数据收集自挪威医学出生登记处和挪威脑瘫质量和监测登记处,涵盖2000年至2016年的活产和围产期死亡。结果显示,非移民母亲的儿童CP患病率较高,随时间的推移呈下降趋势。来自高收入国家的移民母亲的孩子患CP的几率较低,而来自低收入国家的移民母亲的孩子患CP的几率也较低,尽管他们的血缘关系较高,怀孕期间叶酸的使用也较低。中低收入国家母亲的围产期死亡率较高。CP的临床特征在各组之间相似,但低收入国家的儿童智力残疾和脑灰质损伤的发生率更高。
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来源期刊
CiteScore
7.80
自引率
13.20%
发文量
338
审稿时长
3-6 weeks
期刊介绍: Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.
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