Sprouting and network data assessed in the chicken aortic ring assay under stimulation with human adipose-derived stem cell secretomes harvested from single cells or spheroids of different sizes
Petra Wolint , Silvan Hofmann , Julia von Atzigen , Roland Böni , Iris Miescher , Pietro Giovanoli , Maurizio Calcagni , Maximilian Y. Emmert , Johanna Buschmann
{"title":"Sprouting and network data assessed in the chicken aortic ring assay under stimulation with human adipose-derived stem cell secretomes harvested from single cells or spheroids of different sizes","authors":"Petra Wolint , Silvan Hofmann , Julia von Atzigen , Roland Böni , Iris Miescher , Pietro Giovanoli , Maurizio Calcagni , Maximilian Y. Emmert , Johanna Buschmann","doi":"10.1016/j.dib.2025.111371","DOIUrl":null,"url":null,"abstract":"<div><div>The aortic ring assay is widely used to assess the angiogenic modulation evoked by various drugs. However, different parameters are used as readouts and there is no congruence in terminology. In addition, some researchers use one set of parameters, and other researchers choose parameters that overlap to some extent, but miss a part of these parameters, rendering a direct comparison of the readouts and results difficult [1]. Therefore, we present data acquired in the chicken aortic ring assay that cover the full spectrum of possible readouts – exemplified by stimulation with secretomes harvested from human adipose-derived stem cells, cultivated either as single cell monolayer culture or as 3D spheroids, sized 250 cells/spheroid or 8000 cells/spheroid, respectively.</div></div>","PeriodicalId":10973,"journal":{"name":"Data in Brief","volume":"59 ","pages":"Article 111371"},"PeriodicalIF":1.0000,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Data in Brief","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352340925001039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
The aortic ring assay is widely used to assess the angiogenic modulation evoked by various drugs. However, different parameters are used as readouts and there is no congruence in terminology. In addition, some researchers use one set of parameters, and other researchers choose parameters that overlap to some extent, but miss a part of these parameters, rendering a direct comparison of the readouts and results difficult [1]. Therefore, we present data acquired in the chicken aortic ring assay that cover the full spectrum of possible readouts – exemplified by stimulation with secretomes harvested from human adipose-derived stem cells, cultivated either as single cell monolayer culture or as 3D spheroids, sized 250 cells/spheroid or 8000 cells/spheroid, respectively.
期刊介绍：
Data in Brief provides a way for researchers to easily share and reuse each other''s datasets by publishing data articles that: -Thoroughly describe your data, facilitating reproducibility. -Make your data, which is often buried in supplementary material, easier to find. -Increase traffic towards associated research articles and data, leading to more citations. -Open up doors for new collaborations. Because you never know what data will be useful to someone else, Data in Brief welcomes submissions that describe data from all research areas.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
