Assessment of Hemodialysis Adequacy by Online Clearance Monitoring.

Murukeshan Anandi, Muniappan Muthamizh, Suyampirakasam Ilango, Varadharajan Jayaprakash
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Abstract

Measuring the uremic solute clearance is an important factor in analyzing the adequacy of maintenance hemodialysis (MHD) therapy. Conventionally hemodialysis (HD) adequacy was measured by urea removal through the Daugirdas single pool kt/V (spKt/V) formula. We aimed in our study to correlate online clearance monitoring (OCM) spKt/V to the Urea Reduction Ratio (URR) and Daugirdas spKt/V in maintenance hemodialysis patients. This single-center cross-sectional study, conducted at the hemodialysis unit in the nephrology department of SRM Medical College Hospital and Research Center, involved 100 participants undergoing maintenance hemodialysis (MHD) therapy for 200 sessions. The OCM with URR and Daugirdas spKt/V values were obtained from each session and the results were analyzed using SPSS software with p <0.05 significance. In the results, we found that the OCM spKt/V, Daugirdas spKt/V, and URR showed positive correlations. These results emphasize that OCM can be an alternative method to assess dialysis adequacy for every session without the need for repeated blood sampling.

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在线清除率监测评估血液透析充分性。
测量尿毒症溶质清除率是分析维持性血液透析(MHD)治疗是否适当的重要因素。传统的血液透析(HD)充分性是通过Daugirdas单池kt/V (spKt/V)公式去除尿素来测量的。本研究旨在探讨维持性血液透析患者在线清除率监测(OCM) spKt/V与尿素还原比(URR)和Daugirdas spKt/V的相关性。这项单中心横断面研究在SRM医学院附属医院和研究中心肾内科血液透析单元进行,涉及100名接受维持性血液透析(MHD)治疗200次的参与者。各时段的OCM与URR和Daugirdas spKt/V值采用SPSS软件进行统计分析
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
62
期刊介绍: Il Giornale Italiano di Nefrologia (GIN) è la rivista di educazione continua della Società Italiana di Nefrologia SIN ed è pubblicato bimestralmente. E" il più autorevole organo di informazione nefrologia disponibile a livello nazionale. Il giornale Italiano di Nefrologia offre la più aggiornata informazione medico-scientifica rivolta al nefrologo sotto forma di rassegne, casi clinici e articoli finalizzati all’Educazione Continua in Medicina, oltre ai notiziari ed agli atti dei congressi di questa prestigiosa Società Scientifica
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