Silvia Cappelletti, Sara Morales Palomares, Stefano Mancin, Marco Sguanci
{"title":"Successful Unconventional Treatment of Serratia Marcescens Exit-Site Infection in a Central Venous Catheter for Hemodialysis: A Case Report.","authors":"Silvia Cappelletti, Sara Morales Palomares, Stefano Mancin, Marco Sguanci","doi":"10.69097/41-06-2024-06","DOIUrl":null,"url":null,"abstract":"<p><p><b>Introduction.</b> Central Catheter-related infections and biofilm formation are significant issues in the context of nosocomial infections that increase resistance to conventional therapies. <b>Methodology.</b> This case report describes an unconventional treatment for a Serratia Marcescens Central Venous Catheter infection in a hemodialysis patient through the combination of polyguanide and betaine. Clinical evaluations were conducted using the Visual Exit-Site Score and culture swabs. <b>Results.</b> After the first four treatment sessions there was a significant reduction in redness and pain (VES=1); the culture swab at the end of treatment was negative. <b>Conclusions.</b> The results of this case report encourage further research on the effectiveness of non-antibiotic treatments.</p>","PeriodicalId":12553,"journal":{"name":"Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia","volume":"41 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.69097/41-06-2024-06","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction. Central Catheter-related infections and biofilm formation are significant issues in the context of nosocomial infections that increase resistance to conventional therapies. Methodology. This case report describes an unconventional treatment for a Serratia Marcescens Central Venous Catheter infection in a hemodialysis patient through the combination of polyguanide and betaine. Clinical evaluations were conducted using the Visual Exit-Site Score and culture swabs. Results. After the first four treatment sessions there was a significant reduction in redness and pain (VES=1); the culture swab at the end of treatment was negative. Conclusions. The results of this case report encourage further research on the effectiveness of non-antibiotic treatments.
期刊介绍:
Il Giornale Italiano di Nefrologia (GIN) è la rivista di educazione continua della Società Italiana di Nefrologia SIN ed è pubblicato bimestralmente. E" il più autorevole organo di informazione nefrologia disponibile a livello nazionale. Il giornale Italiano di Nefrologia offre la più aggiornata informazione medico-scientifica rivolta al nefrologo sotto forma di rassegne, casi clinici e articoli finalizzati all’Educazione Continua in Medicina, oltre ai notiziari ed agli atti dei congressi di questa prestigiosa Società Scientifica