Successful management of eosinophilic esophagitis with mometasone: an unusual therapeutic approach.

IF 4 4区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-11 DOI:10.17235/reed.2025.11106/2025
Ana Lancho Muñoz, José María López Tobaruela, Paula Iglesias Conejero, Eduardo Redondo Cerezo
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Abstract

Eosinophilic esophagitis is a chronic, immune-mediated esophageal condition characterized by eosinophilic infiltration of the esophageal mucosa. This report discusses the case of a patient with EoE who showed significant clinical and histological improvement following treatment with mometasone, a corticosteroid rare used for this disease. Mometasone has shown promise due to its enhanced mucosal absorption and potent anti-inflammatory properties. In this case, the patient exhibited resolution of symptoms and marked reduction in endoscopic and histological involvement, suggesting that mometasone could serve as a viable alternative therapy in specific clinical scenarios.

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莫米松成功治疗嗜酸性食管炎:一种不寻常的治疗方法。
嗜酸性粒细胞性食管炎是一种慢性、免疫介导的食管疾病,其特征是食管粘膜嗜酸性粒细胞浸润。本报告讨论了一例EoE患者在使用莫米松治疗后表现出显著的临床和组织学改善,莫米松是一种罕见的用于这种疾病的皮质类固醇。莫米松已显示出希望,由于其增强粘膜吸收和有效的抗炎特性。在这个病例中,患者表现出症状的缓解,内窥镜和组织学病变的明显减少,这表明莫米松可以作为一种可行的替代治疗在特定的临床情况下。
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来源期刊
CiteScore
2.00
自引率
25.00%
发文量
400
审稿时长
6-12 weeks
期刊介绍: La Revista Española de Enfermedades Digestivas, Órgano Oficial de la Sociedad Española de Patología Digestiva (SEPD), Sociedad Española de Endoscopia Digestiva (SEED) y Asociación Española de Ecografía Digestiva (AEED), publica artículos originales, editoriales, revisiones, casos clínicos, cartas al director, imágenes en patología digestiva, y otros artículos especiales sobre todos los aspectos relativos a las enfermedades digestivas.
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