Incidence and Factors Associated With Nonunion following Naviculocuneiform Joint Arthrodesis.

IF 2.2 Foot & ankle international Pub Date : 2025-04-01 Epub Date: 2025-02-11 DOI:10.1177/10711007251316556
Jaeyoung Kim, Max Sadlowski, David Vier, Veerabhadra Reddy, Christian Royer, James Brodsky, Jacob Zide
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Abstract

Background: Nonunion following naviculocuneiform (NC) joint arthrodesis is a well-recognized complication. Most studies reporting nonunion rates involve a limited number of cases or focus on a single disease entity. Moreover, there is variation between studies with regard to the number of articular facets included in the arthrodesis as well as the fixation construct used, with no clear evidence indicating how these factors influence union. This study, using the largest cohort to date, aims to investigate the nonunion rate following NC joint arthrodesis and to identify demographic and surgical factors associated with nonunion.

Methods: One hundred ten feet in 100 patients who underwent NC joint arthrodesis between 2016 and 2023 at a single institution were retrospectively identified. The indications for surgery included osteoarthritis (n = 89), deformity (n = 10, flatfoot or cavus), and rheumatoid arthritis (n = 11). Charcot arthropathy was excluded. Nonunions were defined by radiographic review and were further categorized as symptomatic or asymptomatic. Demographic and surgical factors, including isolated medial NC facet vs multiple NC facet arthrodesis, fixation construct, concurrent arthrodesis of other joints, and type of bone graft used, were included in the regression analysis to determine their association with nonunion.

Results: The overall nonunion rate was 27.3% (30/110 cases), with 15.5% (17 cases) presenting as symptomatic nonunions. There were no significant differences in the nonunion rates among different indications for NC arthrodesis (P = .9404). A statistically significant difference in nonunion rates was observed between patients undergoing isolated medial facet arthrodesis (38.2%) and those undergoing multiple facet arthrodesis (16.4%, P = .0102). After performing multivariate analysis adjusted for potential confounders, age (OR 1.08, 95% CI: 1.0-1.16, P = .0456), diabetes (OR 12.70, 95% CI: 1.24-130.3, P = .0324), and isolated medial NC facet arthrodesis (OR 17.48, 95% CI: 3.23-94.54, P = .0009) were significantly associated with nonunion. No significant association with nonunion was identified based on the type of bone graft, fixation construct, or whether concurrent arthrodesis of adjacent foot joints was performed.

Conclusion: This study demonstrates a significant rate of nonunion following NC joint arthrodesis, exceeding that previously reported. We found that the rate of nonunion significantly increased in arthrodeses involving only the medial NC facet as compared to those including multiple NC facets.

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舟状关节融合术后骨不连的发生率及相关因素。
背景:扁平形(NC)关节融合术后不愈合是一种公认的并发症。大多数报告骨不连率的研究涉及的病例数量有限或集中于单一疾病实体。此外,关于关节融合术中包括的关节面数量以及使用的固定结构,研究之间存在差异,没有明确的证据表明这些因素如何影响愈合。本研究使用了迄今为止最大的队列,旨在调查NC关节融合术后的骨不连率,并确定与骨不连相关的人口统计学和外科因素。方法:回顾性分析2016年至2023年在同一机构接受NC关节融合术的100例患者中的110例。手术指征包括骨关节炎(89例)、畸形(10例)、扁平足或弓足)和类风湿关节炎(11例)。排除沙氏关节病。通过影像学检查确定骨不连,并进一步分类为有症状或无症状。人口统计学和外科因素,包括孤立的内侧NC小关节与多个NC小关节关节融合术、固定结构、其他关节同时融合术以及使用的植骨类型,被纳入回归分析,以确定它们与骨不连的关系。结果:总体骨不连率为27.3%(30/110例),其中15.5%(17例)表现为症状性骨不连。不同适应症的NC关节融合术不愈合率无显著差异(P = .9404)。单侧内侧关节突融合术患者的骨不连率(38.2%)与多侧关节突融合术患者(16.4%,P = 0.0102)差异有统计学意义。在对潜在混杂因素进行多因素分析后,年龄(OR 1.08, 95% CI: 1.0-1.16, P = 0.0456)、糖尿病(OR 12.70, 95% CI: 1.24-130.3, P = 0.0324)和孤立的NC内侧小关节关节融合术(OR 17.48, 95% CI: 3.23-94.54, P = 0.0009)与骨不愈合显著相关。根据植骨类型、固定结构或相邻足关节是否同时进行关节融合术,未发现与骨不连有显著关联。结论:本研究表明NC关节融合术后不愈合的发生率显著高于之前的报道。我们发现,与包括多个NC关节面相比,仅涉及内侧NC关节面的关节不愈合率显著增加。
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