Michael R. Duggan, Clare Paterson, Yifei Lu, Hannah Biegel, Heather E. Dark, Jenifer Cordon, Murat Bilgel, Naoto Kaneko, Masaki Shibayama, Shintaro Kato, Makio Furuichi, Iwao Waga, Keita Hiraga, Masahisa Katsuno, Yukiko Nishita, Rei Otsuka, Christos Davatzikos, Guray Erus, Kelsey Loupy, Melissa Simpson, Alexandria Lewis, Abhay Moghekar, Priya Palta, Rebecca F. Gottesman, Susan M. Resnick, Josef Coresh, Stephen A. Williams, Keenan A. Walker
{"title":"The Dementia SomaSignal Test (dSST): A plasma proteomic predictor of 20-year dementia risk","authors":"Michael R. Duggan, Clare Paterson, Yifei Lu, Hannah Biegel, Heather E. Dark, Jenifer Cordon, Murat Bilgel, Naoto Kaneko, Masaki Shibayama, Shintaro Kato, Makio Furuichi, Iwao Waga, Keita Hiraga, Masahisa Katsuno, Yukiko Nishita, Rei Otsuka, Christos Davatzikos, Guray Erus, Kelsey Loupy, Melissa Simpson, Alexandria Lewis, Abhay Moghekar, Priya Palta, Rebecca F. Gottesman, Susan M. Resnick, Josef Coresh, Stephen A. Williams, Keenan A. Walker","doi":"10.1002/alz.14549","DOIUrl":null,"url":null,"abstract":"There is an unmet need for tools to quantify dementia risk during its multi-decade preclinical/prodromal phase, given that current biomarkers predict risk over shorter follow-up periods and are specific to Alzheimer's disease.","PeriodicalId":7471,"journal":{"name":"Alzheimer's & Dementia","volume":"6 1","pages":""},"PeriodicalIF":13.0000,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alzheimer's & Dementia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/alz.14549","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
There is an unmet need for tools to quantify dementia risk during its multi-decade preclinical/prodromal phase, given that current biomarkers predict risk over shorter follow-up periods and are specific to Alzheimer's disease.
期刊介绍：
Alzheimer's & Dementia is a peer-reviewed journal that aims to bridge knowledge gaps in dementia research by covering the entire spectrum, from basic science to clinical trials to social and behavioral investigations. It provides a platform for rapid communication of new findings and ideas, optimal translation of research into practical applications, increasing knowledge across diverse disciplines for early detection, diagnosis, and intervention, and identifying promising new research directions. In July 2008, Alzheimer's & Dementia was accepted for indexing by MEDLINE, recognizing its scientific merit and contribution to Alzheimer's research.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
