Primary unilateral breast angiosarcoma in adolescence

Abstract

Primary breast angiosarcoma is a rare soft tissue malignancy of vascular origin, particularly in young patients. Here, we present the case of an 18-year-old autistic female with Addison's disease who developed a rapidly enlarging unilateral breast mass initially diagnosed as an abscess. Despite treatment, the lesion progressed to chest wall and lymph node metastases within three months. This case emphasizes the importance of including malignancy in the differential diagnosis of atypical breast presentations, even in young patients, and highlights the diagnostic and therapeutic challenges associated with this aggressive tumour.