Synthesis of conjugated dienes through dehydrgeogenative homocoupling reaction of vinyl CH substrates using oxygen as oxidant

Abstract

Palladium-catalyzed green oxidative homocoupling reactions of C_vinylH bonds of terminal alkenes produce conjugated dienes by using O₂ as the crucial oxidant. This method provides an efficient and environmentally compatible approach to 1,3-butadienes under mild conditions, addressing the need for more sustainable reaction processes. Our preliminary results demonstrate the viability of dehydrogenative C_vinylC_vinyl bond-forming processes with molecular oxygen as the sole oxidant, offering a promising strategy for green chemistry applications.