Composition design and performance analysis of binary and ternary Mg-Zn-Ti alloys for biomedical implants

IF 2.2 4区 生物学 Q3 BIOPHYSICS Journal of Biological Physics Pub Date : 2025-02-12 DOI:10.1007/s10867-025-09672-y
Sehrish Mukhtar, Muhammad Kamran, Asima Tayyeb, Faraz Hussain, Muhammad Ishtiaq, Fahad Riaz, Waqas Asghar
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Abstract

Magnesium-based implants are highly valued in the biomedical field for biocompatibility and biodegradability, though their inherent low strength in body fluids is a limitation. This study addresses this by alloying magnesium with zinc and titanium to enhance its properties. Mechanical alloying was used to synthesize binary (Mg-Zn, Mg-Ti) and ternary (Mg-Zn-Ti) alloys, which were then compacted and sintered. The alloy powders, composed of 10 wt% Zn and 5 wt% Ti, were milled at 360 rpm for 10 h. Microstructural analysis revealed uniformly dispersed particles, with SEM confirming spherical and fine particles alongside laminates. XRD identified intermetallic compound formation. The ternary alloy demonstrated superior micro-hardness and Young’s modulus similar to human bone, making it particularly promising for biomedical applications. Incorporating zinc and titanium into the magnesium matrix resulted in a ternary alloy that outperformed its binary counterparts.

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生物医学植入物用二、三元Mg-Zn-Ti合金的成分设计与性能分析
镁基植入物因其生物相容性和生物降解性在生物医学领域受到高度重视,尽管其在体液中固有的低强度是一个限制。本研究通过将镁与锌和钛合金化以提高其性能来解决这一问题。采用机械合金化法制备了二元(Mg-Zn, Mg-Ti)和三元(Mg-Zn- ti)合金,并对其进行压实和烧结。合金粉末由10 wt% Zn和5 wt% Ti组成,在360转/分钟的转速下研磨10小时。显微组织分析显示均匀分散的颗粒,扫描电镜证实了层合板周围的球形和细颗粒。XRD鉴定了金属间化合物的形成。三元合金表现出优异的显微硬度和杨氏模量,与人骨相似,使其在生物医学应用方面特别有前景。将锌和钛结合到镁基体中产生的三元合金性能优于二元合金。
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来源期刊
Journal of Biological Physics
Journal of Biological Physics 生物-生物物理
CiteScore
3.00
自引率
5.60%
发文量
20
审稿时长
>12 weeks
期刊介绍: Many physicists are turning their attention to domains that were not traditionally part of physics and are applying the sophisticated tools of theoretical, computational and experimental physics to investigate biological processes, systems and materials. The Journal of Biological Physics provides a medium where this growing community of scientists can publish its results and discuss its aims and methods. It welcomes papers which use the tools of physics in an innovative way to study biological problems, as well as research aimed at providing a better understanding of the physical principles underlying biological processes.
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