Ms. Melody Cai-Syaun Wu, Mr. Jack Hau-Ting Wei, Mr. Ricky Yu-Syun Fan, Ms. Eng Zhi Sim, Prof. Ken-Tye Yong, Prof. Tianxun Gong, Prof. Kien Voon Kong
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引用次数: 0
Abstract
Exciting breakthrough in neuroprotective phototherapy! Introducing Bpy-BODIPY@Au, a cutting-edge nanophotosensitizer designed to enhance treatment for neurodegenerative diseases. By using the J-aggregation of BODIPY on gold nanourchins, this innovative structure boosts singlet oxygen production and photostability, effectively reducing tau protein aggregation—a key factor in Alzheimer′s disease. This promising therapeutic approach expands the use of BODIPY-based nanoagents in treating neurodegenerative conditions, showcasing their potential for durable and targeted phototherapy. More details can be found in article 10.1002/cbic.202400562 by Ken-Tye Yong, Tianxun Gong, Kien Voon Kong, and co-workers.
期刊介绍：
ChemBioChem (Impact Factor 2018: 2.641) publishes important breakthroughs across all areas at the interface of chemistry and biology, including the fields of chemical biology, bioorganic chemistry, bioinorganic chemistry, synthetic biology, biocatalysis, bionanotechnology, and biomaterials. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and supported by the Asian Chemical Editorial Society (ACES).
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