Outcomes of a Tenon Patch Graft for Corneal Perforations in Resolving Infectious Keratitis.

IF 2.1 3区 医学 Q2 OPHTHALMOLOGY Cornea Pub Date : 2026-01-01 Epub Date: 2025-02-11 DOI:10.1097/ICO.0000000000003834
Aniruddh Heroor, Prajakta Dandekar, Somasheila I Murthy
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Abstract

Purpose: To report the outcomes of a Tenon patch graft (TPG) in sealing corneal perforations in cases with resolving infectious keratitis.

Methods: This retrospective interventional study was conducted at a tertiary eye care center. All patients who underwent a TPG for corneal perforations because of clinically or/and microbiologically diagnosed infectious keratitis between 2021 and 2023 were included. The surgical technique was consistent with that used in noninfective etiology. Out of 100 cases undergoing a TPG during the same period, 15 eyes of 14 patients had corneal perforations secondary to infectious keratitis.

Results: The etiological profile included bacterial keratitis in 8, viral and fungal keratitis in 3, and Pythium keratitis in 1 eye of 15 eyes. One patient had bilateral infectious keratitis after refractive surgery. The perforations were central in 7 and paracentral in 8 eyes. Successful restoration of tectonic integrity at 1 month was achieved in 14/15 eyes (93%). One patient had a repeat perforation at 3 weeks postoperatively, which was managed with a cyanoacrylate glue application. Infection control was achieved in all cases with adjunctive topical antimicrobial therapy.

Conclusions: A TPG is a viable option for restoring globe integrity in corneal perforations encountered in resolving infectious keratitis.

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角膜穿孔用榫补片治疗感染性角膜炎的疗效。
目的:报道在解决感染性角膜炎的情况下,用榫补片(TPG)封堵角膜穿孔的结果。方法:回顾性介入研究在某三级眼科保健中心进行。所有在2021年至2023年间因临床或/和微生物学诊断为感染性角膜炎而接受TPG治疗角膜穿孔的患者均被纳入研究。手术技术与非感染性病因一致。在同一时期进行TPG的100例患者中,14例患者中有15只眼睛出现继发于感染性角膜炎的角膜穿孔。结果:细菌性角膜炎8例,病毒性和真菌性角膜炎3例,角膜炎1例(15眼)。1例患者在屈光手术后出现双侧感染性角膜炎。7眼为中心孔,8眼为中心旁孔。1个月后,14/15只眼(93%)的构造完整性恢复成功。1例患者术后3周再次穿孔,应用氰基丙烯酸酯胶处理。所有病例的感染均在局部抗菌药物辅助治疗下得到控制。结论:在解决感染性角膜炎时,TPG是恢复角膜穿孔完整的可行选择。
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来源期刊
Cornea
Cornea 医学-眼科学
CiteScore
5.20
自引率
10.70%
发文量
354
审稿时长
3-6 weeks
期刊介绍: For corneal specialists and for all general ophthalmologists with an interest in this exciting subspecialty, Cornea brings together the latest clinical and basic research on the cornea and the anterior segment of the eye. Each volume is peer-reviewed by Cornea''s board of world-renowned experts and fully indexed in archival format. Your subscription brings you the latest developments in your field and a growing library of valuable professional references. Sponsored by The Cornea Society which was founded as the Castroviejo Cornea Society in 1975.
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