Junctional proliferative vitreoretinopathy in rhegmatogenous retinal detachment secondary to viral retinitis in HIV.

IF 1.4 4区 医学 Q3 OPHTHALMOLOGY International Ophthalmology Pub Date : 2025-02-11 DOI:10.1007/s10792-025-03448-y
Anup Kelgaonkar, Anamika Patel, Avinash Pathengay
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Abstract

Introduction: Rhegmatogenous retinal detachment (RRD) is a vision-threatening complication of viral retinitis, at times compounded by proliferative vitreoretinopathy (PVR) at the junction of the necrotic and unaffected retina.

Methods: Retrospective review of eyes with 'junctional PVR' in RRD after viral retinitis. We define junctional PVR as presence of stiffness, transverse traction, epiretinal membrane and/or pucker at the junction of normal and necrotic retina.

Results: Five eyes of four patients with a mean age at presentation of 46.5 ± 10.96 years were included. Immunosuppression due to Human immunodeficiency virus (HIV) was the underlying condition in all the cases. Posterior hyaloid removal and epiretinal membrane removal at the junctional PVR was performed in all cases. Favourable outcomes were observed in seven sites where epiretinal membrane (ERM) removal with inner limiting membrane (ILM) peeling was performed; however, one site developed localised RRD requiring re-surgery. The mean logMAR best-corrected visual acuity (BCVA) improved from 1.84 before surgery to 0.64 during the last follow-up. All patients had undergone 23 G vitrectomy and silicone oil tamponade 1500 Centistokes (cSt) was used in all patients for a mean duration of 6.8 months.

Conclusion: Management of posterior hyaloid coupled with ERM removal and localised ILM peeling may be used to address junctional PVR in the eyes with RRD after viral retinitis.

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HIV病毒性视网膜炎继发于孔源性视网膜脱离的结缔组织增生性玻璃体视网膜病变。
孔源性视网膜脱离(RRD)是一种威胁视力的病毒性视网膜炎并发症,有时在坏死和未受影响的视网膜交界处合并增生性玻璃体视网膜病变(PVR)。方法:回顾性分析病毒性视网膜炎后RRD出现“结膜性PVR”的眼。我们将交界性PVR定义为在正常视网膜和坏死视网膜交界处出现僵硬、横向牵引、视网膜前膜和/或皱起。结果:纳入4例患者5只眼,平均发病年龄46.5±10.96岁。由于人类免疫缺陷病毒(HIV)引起的免疫抑制是所有病例的潜在条件。所有病例均行后玻璃体切除和视网膜前膜切除。在视网膜前膜(ERM)去除和内限制膜(ILM)剥离的7个部位观察到良好的结果;然而,一个部位发生了局部RRD,需要再次手术。平均logMAR最佳矫正视力(BCVA)从手术前的1.84改善到最后一次随访时的0.64。所有患者均行23g玻璃体切除术,使用硅油填塞1500 Centistokes (cSt),平均持续时间6.8个月。结论:病毒性视网膜炎后视网膜玻璃体治疗联合ERM切除和局部ILM剥离可有效解决RRD眼交界性PVR。
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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
451
期刊介绍: International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.
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