Visual Outcomes following implantation of a non-diffractive extended depth of focus Intraocular Lens in patients with early dry macular degeneration.

Abstract

Purpose: Evaluate visual outcomes following implantation of a non-diffractive extended deapth of focus (EDOF) intraocular lens (IOL) in patients with early dry age-related macular degeneration (AMD).

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Design: Prospective, interventional series.

Methods: Patients undergoing cataract surgery with the EDOF Acrysof Vivity IOL and having early dry AMD were included. Primary outcome measures were monocular unaided and corrected distance visual acuity (UDVA, CDVA) 3 months postoperatively. Secondary outcome measures were: monocular unaided and distance corrected intermediate (UIVA, DCIVA) (66cm) and near (UNVA, DCNVA) (40cm) visual acuity as well as mesopic contrast sensitivity (CS).

Results: 40 eyes (40 patients) with a mean age of 68.5 + 8.38 (standard deviation, SD) years were included. UDVA and CDVA at 3 months follow up were 0.12 + 0.07 and 0.10 + 0.10 (SD) LogMAR. UIVA, DCIVA were 0.25 + 0.09, 0.12 + 0.09 LogMAR. UNVA, DCNVA were 0.23 + 0.10, 0.19 + 0.15 LogMAR. Mesopic CS values without glare were 1.50 + 0.10, 1.69 + 0.26, 1.40 + 0.30 and 0.84 + 0.5 units at 3, 6, 12 and 18 cycles per degree (CPD). Mesopic CS with glare was 1.53 + 0.16, 1.63 + 0.21, 1.21 + 0.45 and 0.75 + 0.42 units.

Conclusion: The Acrysof Vivity IOL gives very good distance visual acuity with improved intermediate and near visual acuity without significant compromise in contrast sensitivity in eyes with early dry AMD.