MXene-Derived Multifunctional Biomaterials: New Opportunities for Wound Healing.

IF 9.6 Q1 ENGINEERING, BIOMEDICAL Biomaterials research Pub Date : 2025-02-11 eCollection Date: 2025-01-01 DOI:10.34133/bmr.0143

Dong Luo, Hui-Qi Zhang, Xin-Yang Xuanyuan, Dan Deng, Zheng-Mao Lu, Wen-Shang Liu, Meng Li

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Abstract

The process of wound healing is frequently impeded by metabolic imbalances within the wound microenvironment. MXenes exhibit exceptional biocompatibility, biodegradability, photothermal conversion efficiency, conductivity, and adaptable surface functionalization, demonstrating marked potential in the development of multifunctional platforms for wound healing. Moreover, the integration of MXenes with other bioactive nanomaterials has been shown to enhance their therapeutic efficacy, paving the way for innovative approaches to wound healing. In this review, we provide a systematic exposition of the mechanisms through which MXenes facilitate wound healing and offer a comprehensive analysis of the current research landscape on MXene-based multifunctional bioactive composites in this field. By delving into the latest scientific discoveries, we identify the existing challenges and potential future trajectories for the advancement of MXenes. Our comprehensive evaluation aims to provide insightful guidance for the formulation of more effective wound healing strategies.

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mxene衍生的多功能生物材料：伤口愈合的新机遇。

伤口愈合过程经常受到伤口微环境内代谢不平衡的阻碍。MXenes具有优异的生物相容性、可生物降解性、光热转换效率、导电性和适应性表面功能化，在伤口愈合的多功能平台开发中显示出显著的潜力。此外，MXenes与其他生物活性纳米材料的整合已被证明可以提高其治疗效果，为伤口愈合的创新方法铺平了道路。在这篇综述中，我们对MXenes促进伤口愈合的机制进行了系统的阐述，并对该领域基于MXenes的多功能生物活性复合材料的研究现状进行了全面的分析。通过深入研究最新的科学发现，我们确定了MXenes发展的现有挑战和潜在的未来轨迹。我们的综合评价旨在为制定更有效的伤口愈合策略提供有见地的指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biomaterials research

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